Results 71 to 80 of about 3,052,418 (362)
Alternative uses for tannery wastes: a review of environmental, sustainability, and science
Journal of Leather Science and Engineering, 2020 The manufacture of leather covers a wide productive chain and beyond contributes to the economic flow. The various stages of leather processing result in high volumes of solid waste.
Cesar Vinicius Toniciolli Rigueto +6 more
doaj +1 more source
Psychophysiological modelling and the measurement of fear conditioning [PDF]
, 2020 Quantification of fear conditioning is paramount to many clinical and translational studies on aversive learning. Various measures of fear conditioning co-exist, including different observables and different methods of pre-processing.
Bach, D., Melinscak, F.
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Fear Conditioning and Extinction: Examining the Role of GSK3β ser 389 [PDF]
, 2016 GSK3β is a serine threonine kinase that has been shown to influence numerous biological and psychological interactions, including the regulation of cell survival and cell death, as well as influencing mood disorders such as major depressive disorder and ...
Liebman, Benjamin
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Intestinal-type adenocarcinoma of the vulva: A case study
Gynecologic Oncology Reports, 2019 Approximately 5% of all gynecologic cancers are of the vulva, of which 90% are squamous cell in origin. Adenocarcinomas of the vulva are extremely infrequent with most relating to epithelial glands in the vulvar region.
Brian Kaltenecker +3 more
doaj +1 more source
Role of p38 MAPK inhibitor in conditioned fear [PDF]
, 2015 p38 mitogen activated protein kinase (p38) is a kinase that has been implicated in cellular plasticity, stress, and psychiatric disorders and recently in the process of DNA repair.
Bauman, Brittany Nicole +1 more
core +1 more source
From extinction learning to anxiety treatment: mind the gap [PDF]
, 2019 Laboratory models of extinction learning in animals and humans have the potential to illuminate methods for improving clinical treatment of fear-based clinical disorders.
Carpenter, Joseph K. +2 more
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source