Results 81 to 90 of about 2,961,599 (361)

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

open access: yesFEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti   +8 more
wiley   +1 more source

Neither to Praise nor to Bury, Simply to Remember? In Memory of Michael Scriven

open access: yesJournal of MultiDisciplinary Evaluation
A remembrance of Michael Scriven and his, sometimes perplexing, understanding of and contributions to evaluation.
William Fear
doaj   +1 more source

The NASA broad-specification fuels combustion technology program: An assessment of phase 1 test results [PDF]

open access: yes
An assessment is made of the results of Phase 1 screening testing of current and advanced combustion system concepts using several broadened-properties fuels. The severity of each of several fuels-properties effects on combustor performance or liner life
Fear, J. S.
core   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Performance of an annual combustor designed for a low-cost turbojet engine [PDF]

open access: yes
Performance tests were conducted on a combustor designed for use in a low-cost turbojet engine. Low-cost features included the use of very inexpensive simplex fuel nozzles and combustor liners of perforated sheet material.
Fear, J. S.
core   +1 more source

Fear and Firearms [PDF]

open access: yes, 2017
Reviewing: MICHAEL WALDMAN, THE SECOND AMENDMENT: A BIOGRAPHY (SIMON & SCHUSTER 2014); FIRMIN DEBRABANDER, DO GUNS MAKE US FREE? DEMOCRACY AND THE ARMED SOCIETY (YALE UNIVERSITY PRESS 2015)
Miller, Darrell A. H.
core   +2 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Banks on Board [PDF]

open access: yes
As part of a series of related papers, the authors examine the conceptual foundations of German and American corporate governance, specifically highlighting the role of banks' relationships to corporations and the stock market.
Christopher Kobrak, Jeffrey Fear
core  

Associations between Feeling and Judging the Emotions of Happiness and Fear: Findings from a Large-Scale Field Experiment [PDF]

open access: yes, 2010
Background: How do we recognize emotions from other people? One possibility is that our own emotional experiences guide us in the online recognition of emotion in others.
Adolphs, Ralph   +2 more
core   +5 more sources

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

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