Results 101 to 110 of about 637,566 (254)

Smartphone‐Guided Visible Light Modulation of RSNOs for Antimicrobial Activity via Controlled Nitric Oxide Release

open access: yesAdvanced Science, EarlyView.
A light‐activated catheter insert combines antimicrobial blue light with nitric oxide release to generate complementary oxidative and nitrosative stress, producing potent broad‐spectrum antimicrobial activity. The approach achieves greater than 4‐log reductions in bacterial and fungal viability and significantly reduces Staphylococcus aureus ...
Alexander Bruckmann   +7 more
wiley   +1 more source

Vine‐Inspired Soft Robotics: Materials, Actuations, and Emerging Applications

open access: yesAdvanced Science, EarlyView.
Vine‐inspired robots grow from the tip, enabling navigation through confined spaces with minimal disturbance. This Review summarizes material and actuation strategies for vine‐inspired growth, key functions including steering, retraction, attachment, branching, and variable stiffness, and emerging applications spanning medical intervention, confined ...
Jiahao Wu   +7 more
wiley   +1 more source

Molecular Preorganization Unlocks Reversible Solid‐State Photoconversion in Dianthrylnaphthalene‐Based Molecular Solar Thermal Systems

open access: yesAngewandte Chemie, EarlyView.
Three dianthrylnaphthalenes were synthesized and investigated for molecular solar thermal (MOST) energy storage. Naphthyl‐based bridging units preorganize the two anthracene moieties face‐to‐face, leading to improved photoisomerization quantum yield (QY) and unlocked bidirectional photoswitching in the solid state compared to previously reported ortho ...
Nicolò Baggi   +10 more
wiley   +2 more sources

Uncertainty-Dependent Extinction of Fear Memory in an Amygdala-mPFC Neural Circuit Model.

open access: yesPLoS Computational Biology, 2016
Uncertainty of fear conditioning is crucial for the acquisition and extinction of fear memory. Fear memory acquired through partial pairings of a conditioned stimulus (CS) and an unconditioned stimulus (US) is more resistant to extinction than that ...
Yuzhe Li   +3 more
doaj   +1 more source

Reduced expression of conditioned fear in the R6/2 mouse model of Huntington's disease is related to abnormal activity in prelimbic cortex

open access: yesNeurobiology of Disease, 2011
Prefrontal cortex (PFC) dysfunction is common in patients with Huntington's disease (HD), a dominantly inherited neurological disorder, and has been linked to cognitive disruption.
Adam G. Walker   +2 more
doaj   +1 more source

Response-specific sex difference in the retention of fear extinction

open access: yes, 2017
Fear conditioning studies in rodents allow us to assess vulnerability factors which might underlie fear-based psychopathology such as post-traumatic stress disorder (PTSD).
Meagan E. Voulo, Ryan G. Parsons
core   +1 more source

Sarbecoviruses Suppress Innate Immunity by Recruiting PPM1A to Modulate STAT2 and ORF9b Phosphorylation

open access: yesAdvanced Science, EarlyView.
Sarbecovirus ORF9b recruits host phosphatase PPM1A to suppress innate immunity through dual mechanisms. PPM1A directly dephosphorylates ORF9b to sustain its activity and indirectly downregulates STAT2 phosphorylation to impair interferon signaling. Pharmacological inhibition of PPM1A restores antiviral responses and limits sarbecovirus replication ...
Lixiang Xie   +24 more
wiley   +1 more source

Mechanistic Control of Cathode–Electrolyte Interphase Formation in Gel Polymer Electrolyte for Lithium‐Ion Batteries

open access: yesAngewandte Chemie, EarlyView.
To regulate a distinct degradation pathway introduced by residual monomers in in‐situ gel polymer electrolytes (GPEs), tris(4‐fluorophenyl)phosphine (TFPP) is coupled with a voltage hold (VH) protocol. TFPP first covers the high‐Ni cathode surface and then preferentially decomposes during the hold step, forming a cathode–electrolyte interphase (CEI ...
Sang Goo Kang   +4 more
wiley   +2 more sources

Fire‐Safe Hierarchical Solid Polymer Electrolytes Enabled by Dual‐Functional Microcapsules for Lithium Metal Batteries

open access: yesAdvanced Science, EarlyView.
Dual‐functional fire‐safe microcapsules are integrated into hierarchical solid polymer electrolytes to provide sequential protection against thermal abuse. The ammonium hydrogen phytate‐modified shell forms a protective char barrier, while the thermally triggered release of perfluoro(2‐methyl‐3‐pentanone) actively suppresses combustion, enabling safer ...
Ziqi Huang   +5 more
wiley   +1 more source

No Evidence for Decreased Generalization of Fear Extinction in High-Trait Anxious Individuals

open access: yesJournal of Experimental Psychopathology
Exposure-based therapy for anxiety disorders involves confrontations with feared but innocuous stimuli to promote inhibitory safety learning and fear extinction.
Bart Endhoven   +3 more
doaj   +1 more source

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