Results 61 to 70 of about 176,132,754 (255)

The relationship of dental caries and dental fear in Malaysian adolescents: a latent variable approach [PDF]

, 2014
This paper is funded by University Malaya.Background To investigate the role of geography (place of residence) as a moderator in the relationship between dental caries disease and treatment experience and dental fear in 16-year-olds living in Malaysia ...
Humphris, Gerry, Leng Ong, Ali, Esa, Rashidah, Esa, R., Humphris, G., Humphris, Gerald Michael, Ong, Ai Leng, Freeman, Ruth, Ong, A.L., Freeman, R., Ruth Freeman, Rashidah Esa, Ai Leng Ong, Gerry Humphris, Humphris, Gerald Michael; id_orcid   +14 more
core   +2 more sources

Lorlatinib‐Containing Therapy for MYCN‐Amplified, ALK‐Mutated Neuroblastoma With Bulky Leptomeningeal Relapse: A Case Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Central nervous system (CNS) relapse of neuroblastoma carries a poor prognosis, and craniospinal irradiation (CSI) poses substantial long‐term toxicity in young children. We report a toddler with MYCN‐amplified neuroblastoma harboring somatic ALK R1275Q who developed extensive leptomeningeal relapse with paraplegia.
Jinwoo Kim, Minji Kim, Nani Jung, Sung Eun Kim, Ji Yoon Kim, Mi Ae Chu, Jung Eun Kwon, Yeo Hyang Kim, So Mi Lee, Ki‐Su Park, Jeong Eun Lee, Ye Jee Shim   +11 more
wiley   +1 more source

Fear of progression.

, 2014
Fear of progression (or fear of recurrence) is an appropriate, rational response to the real threat of cancer and cancer treatments. However, elevated levels of fear of progression can become dysfunctional, affecting well-being, quality of life, and ...
Herschbach, Peter;Dinkel, Andreas
core   +1 more source

The relationship between perceived social support and health-promoting behaviors among middle-aged and young patients after PCI: the mediating role of fear of disease progression

Frontiers in Public Health
ObjectiveThis study aims to investigate the mediating role of fear of disease progression in the relationship between perceived social support and health-promoting behaviors among middle-aged and young patients after PCI, providing a theoretical basis ...
Yuxin Li, Xiaoli Zhong, Tianxia Zhao, Ping Dai, Junrong Yang, Yuting Fan, Jijun Wu, Lin He   +7 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Correlation of fear of disease progression between patients with chronic kidney and their spouses

Huli yanjiu, 2019
ObjectiveTo probe into the correlation of the fear of disease progression between patients with chronic kidney disease and their spouses.MethodsA total of 136 non⁃dialysis patients with chronic kidney disease and their spouses were taken an inquiry by ...
LI Yanyan, SHAN Yan, DU Liping, ZHOU Yue, JIANG Tingting, CAI Li   +5 more
doaj  

Analysis on status of fear of disease progression in patients with nasopharyngeal carcinoma after 5 years discharged from hospital and its influencing factors

Huli yanjiu, 2020
ObjectiveThis paper investigated status quo on fear of disease progression in nasopharyngeal carcinoma patients after 5 years discharged from hospital,and analyzed its influencing factors.MethodsA total of 100 nasopharyngeal carcinoma patients(NPC ...
QIU Liyan, YANG Li
doaj  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A cross-sectional study on fear of progression in patients with myasthenia gravis

Scientific Reports
Patients with myasthenia gravis (MG) are prone to resulting in a significant psychological burden. This study aims to investigate the condition of fear of progression (FoP) and identify factors associated with FoP among MG patients.
Si Luo, Ying Xiong, Ziwei Song, Jia Lian, Yusen Qiu, Min Zhu, Menghua Li, Meihong Zhou, Daojun Hong   +8 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source