Results 121 to 130 of about 794,118 (307)

Fear of Missing Out (FoMO): A Current Review

Psikiyatride Güncel Yaklaşımlar, 2021
Son zamanlarda, insanlar arası iletişim ve etkileşimin büyük çoğunluğunun internet ve mobil cihazlar aracılığıyla gerçekleştirilmesi ve yaygın sosyal medya kullanımı, insanlara belli avantajlar sağlamanın yanı sıra yeni olumsuzluklar da katmaktadır. Alan yazında Fear of Missing Out (FoMO) olarak adlandırılan, Türkçeye Gelişmeleri Kaçırma Korkusu (GKK ...
TANHAN, Fuat, ÖZOK, Halil İbrahim, TAYİZ, Volkan   +2 more
openaire   +3 more sources

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Fear of missing out (FoMO) and internet addiction among adolescence: The moderation effect of gender differences

Humanitas: Indonesian Psychological Journal
The use of the internet and its impact on adolescents is an increasingly important topic in the current digital era. This study explores the moderating role of gender in the relationship between Fear of Missing Out (FoMO) and internet addiction among ...
Martaria Rizky Rinaldi
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

PENGARUH REGULASI DIRI AKADEMIK TERHADAP ONLINE FEAR OF MISSING OUT SISWA SMK [PDF]

Online Fear of Missing Out isa huge concern about not being able to access social media. One of the causes of on-fomo is academic self-regulation. Academic self-regulation can affect on-fomo because it can help people learn how to manage social media and
Rafif, Salsabila
core  

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Homebound: STS-M1301 A Study on Television Writing in the Science Fiction Genre [PDF]

, 2019
This project is a scene-by-scene outline of an original television pilot script in the science fiction genre. The outline is based on research conducted in both the television and science fiction fields, providing the project with a firm foundation in ...
Crouch, Matthew
core   +1 more source