Results 131 to 140 of about 805,309 (392)

Resilience and symptoms of depression and anxiety in adolescents: the mediating role of fear of missing out

open access: yesCurrent Issues in Personality Psychology
Background This research aimed to determine the relationship of resilience and symptoms of depression and anxiety in Indonesian adolescents, particularly the degree to which the fear of missing out (FoMO) influenced resilience toward symptoms of ...
Annastasia Ediati   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Stranger Danger! [PDF]

open access: yes, 2018
This article discusses the historical origins of the “stranger danger” myth, including the conditions that fueled the spread of panic. It explains how the myth was bolstered by increased media coverage, emotional appeals by parents, and public awareness ...
Wodda, Aimee
core   +1 more source

Nurses’ Experiences Empowering Hospitalized Patients [PDF]

open access: yes, 2017
Four focus groups were conducted to explore acute care nurses’ experiences empowering patients and the facilitators and barriers they encountered during the process.
Bull, Margaret J., Jerofke-Owen, Teresa
core   +2 more sources

Phubbing as a Social Norm: Effects on Fear of Missing Out (FoMO) and Perceived Exclusion

open access: yesRevista Latinoamericana de Tecnología Educativa
Technology and social media have transformed the way we communicate, interact, and stay informed. Phubbing is a term that comes from two words «phone» and «snubbing» and represents the act of ignoring a person in a real life setting by paying attention ...
Miguel Ángel Albalá-Genol   +3 more
semanticscholar   +1 more source

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