Results 111 to 120 of about 483,021 (202)

Acoustic startle and fear‐potentiated startle in rats selectively bred for fast and slow kindling rates: relation to monoamine activity

, 2000
The acoustic startle response, prepulse inhibition, fear-potentiated startle and monoamine activity induced by either, a novel stimulus or a cue previously paired with foot-shock (fear-conditioning), were assessed in rats selectively bred for differences
Merali, Zul, Shawn Hayley, Hayley, Shawn, Hymie Anisman, Anisman, Hymie, Owen Kelly, Borowski, Thomas, Zul Merali, McIntyre, Dan C, Thomas Borowski, Dan C. McIntyre, Owen, Kelly   +11 more
core   +1 more source

Fear conditioning following unilateral temporal lobectomy : dissociation of conditioned startle potentiation and autonomic learning

, 2005
The present study investigated fear-potentiated startle and autonomic learning in brain-lesioned patients in a classical fear-conditioning paradigm. Startle blink and skin conductance responses of 30 patients who underwent unilateral temporal lobectomy ...
Schroeder, Henry W. S., Runge, Uwe, Kessler, Christof, Weike, Almut I., Hamm, Alfons, Schupp, Harald T.   +5 more
core   +1 more source

Associations between PACAP levels and psychophysiological indicators of fear and arousal in adults with posttraumatic stress symptoms

Journal of Mood and Anxiety Disorders
Posttraumatic stress disorder (PTSD) is associated with heightened fear responding and decreased fear regulation, as demonstrated with psychophysiological measures (e.g., autonomic function) and circulating biomarkers of stress, such as pituitary ...
Antonia V. Seligowski, Kevin J. Clancy, Eylül Akman, Michael Lewis, Victor May, Caitlin Ravichandran, Sydney A. Jobson, Daniel E. Bradford, Sayamwong E. Hammack, William A. Carlezon, Jr., Kerry J. Ressler, Scott L. Rauch, Isabelle M. Rosso   +12 more
doaj   +1 more source

Involvement of subcortical and cortical afferents to the lateral nucleus of the amygdala in fear conditioning measured with fear- potentiated startle in rats trained concurrently with auditory and visual conditioned stimuli

, 1995
The goal of this work was to test the involvement, in fear conditioning, of afferents to the lateral nucleus of the amygdala originating from the auditory thalamus, auditory cortex, and perirhinal area.
M Davis, S Campeau
core   +1 more source

An Examination of an Alternative Use for the Fear-Potentiated Startle Paradigm and the Effects of Angiotensin Type 1 Receptor Inhibition on Extinction Learning

, 2019
Background – PTSD is a chronic and debilitating mental illness with limited available treatments. New medications, including Angiotensin Type 1 Receptor inhibitors, have been found to improve extinction learning retention in rodents and could be a means ...
Seidenberg, Jessica
core   +1 more source

Facilitation of Conditioned Fear Extinction by Systemic Administration or Intra-Amygdala Infusions of d-Cycloserine as Assessed with Fear-Potentiated Startle in Rats

, 2002
NMDA receptor antagonists block conditioned fear extinction when injected systemically and also when infused directly into the amygdala. Here we evaluate the ability ofd-cycloserine (DCS), a partial agonist at the strychnine-insensitive glycine ...
Michael Davis, Kwok-Tung Lu, David L. Walker, Kerry J. Ressler   +3 more
core   +1 more source

The Investigation of the Novel Peptide TUF1 in Fear Potentiated Startle

, 2011
The goal of this study is to determine the role of TUF1 and to measure if the administration of this peptide into the ventricles alters fear responses by affecting the acquisition and/or expression of acoustic startle.Additional contributors: Jiva Dimova;
Reise, Kathryn
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Psychophysiological treatment outcomes: Corticotropin-releasing factor type 1 receptor antagonist increases inhibition of fear-potentiated startle in PTSD patients. [PDF]

Psychophysiology, 2020
Jovanovic T, Duncan EJ, Kaye J, Garza K, Norrholm SD, Inslicht SS, Neylan TC, Mathew SJ, Iosifescu D, Rothbaum BO, Mayberg HS, Dunlop BW.   +11 more
europepmc   +1 more source

Attenuating human fear memory retention with minocycline: a randomized placebo-controlled trial

Translational Psychiatry
Pavlovian fear conditioning is widely used as a pre-clinical model to investigate methods for prevention and treatment of anxiety and stress-related disorders.
Yanfang Xia, Jelena Wehrli, Aslan Abivardi, Madalina Hostiuc, Birgit Kleim, Dominik R. Bach   +5 more
doaj   +1 more source

ASSESSMENT OF NEUROTENSIN RECEPTOR AGONIST EFFECTS ON FEAR-POTENTIATED STARTLE [PDF]

, 2016
Systemic administration of the NTS1 receptor agonist PD149163 has exhibited anxiolytic effects in male rats. The present study sought to further evaluate the potential anxiolytic effects of PD149163 by assessing this compound in both male and female ...
Vanden Avond, Mark Aaron
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