Results 61 to 70 of about 1,866,866 (289)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

A Double-Layered Covered Biliary Metal Stent for the Management of Unresectable Malignant Biliary Obstruction: A Multicenter Feasibility Study

Gut and Liver, 2016
Background/AimsThe covered self-expandable metal stent (CMS) was developed to prevent tumor ingrowth-induced stent occlusion during the treatment of malignant biliary obstruction.
Jin-Seok Park, Seok Jeong, Don Haeng Lee, Jong Ho Moon, Kyu Taek Lee, Seok Ho Dong   +5 more
doaj   +1 more source

Entrainer selection for pressure swing batch distillation [PDF]

, 2008
The feasibility of the separation of binary homoazeotropes with pressure swing batch distillation by the application of an entrainer is studied. The feasibility studies are based on the assumption of maximal separation and on the analysis of batch ...
Kopasz, Árpád, Láng, Péter, Modla, Gábor   +2 more
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Feasibility and constraints of Bragg peak FLASH proton therapy treatment planning

Frontiers in Oncology
IntroductionFLASH proton therapy (FLASH-PT) requires ultra-high dose rate (≥ 40 Gy/s) protons to be delivered in a short timescale whilst conforming to a patient-specific target. This study investigates the feasibility and constraints of Bragg peak FLASH-
Nathalie Lövgren, Ingrid Fagerström Kristensen, Ingrid Fagerström Kristensen, Kristoffer Petersson, Kristoffer Petersson   +4 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Doppler ultrasound surveillance of recently formed haemodialysis arteriovenous fistula: the SONAR observational cohort study

Health Technology Assessment
Background Arteriovenous fistulas are considered the best option for haemodialysis provision, but as many as 30% fail to mature or suffer early failure. Objective To assess the feasibility of performing a randomised controlled trial that examines whether,
James Richards, Dominic Summers, Anna Sidders, Elisa Allen, Mohammed Ayaz Hossain, Subhankar Paul, Matthew Slater, Matthew Bartlett, Regin Lagaac, Emma Laing, Valerie Hopkins, Chloe Fitzpatrick-Creamer, Cara Hudson, Joseph Parsons, Samuel Turner, Andrew Tambyraja, Subash Somalanka, James Hunter, Sam Dutta, Neil Hoye, Sarah Lawman, Tracey Salter, Mohammed Farid Aslam, Atul Bagul, Rajesh Sivaprakasam, George E Smith, Helen L Thomas, Zia Moinuddin, Simon R Knight, Nicholas Barnett, Reza Motallebzadeh, Gavin J Pettigrew   +31 more
doaj   +1 more source

Feasibility and clinical integration study on low⁃cost digital gait analysis system based on dual Kinect V2

Chinese Journal of Contemporary Neurology and Neurosurgery
Objective To develop a low⁃cost digit⁃intelligent gait analysis system based on dual Kinect V2 sensors and universal open⁃source software platforms (DKS), and to evaluate its feasibility and accuracy for gait analysis. Methods A total of 15 patients with
ZHANG Shi⁃yu, CHEN Guo⁃rong, MAIMAITIABULA Saimaiti, XU Xing⁃hua, ZHUANG Jia⁃shu, CHEN Xiao⁃lei   +5 more
doaj   +1 more source

A weight management programme for fathers of children aged 4–11 years: cultural adaptation and the Healthy Dads, Healthy Kids UK feasibility RCT

Public Health Research, 2020
Background: More men than women in the UK are living with overweight or obesity, but men are less likely to engage with weight loss programmes. Healthy Dads, Healthy Kids is an effective Australian weight management programme that targets fathers, who ...
Kate Jolly, Tania Griffin, Manbinder Sidhu, Peymane Adab, Adrienne Burgess, Clare Collins, Amanda Daley, Andrew Entwistle, Emma Frew, Pollyanna Hardy, Kiya Hurley, Laura Jones, Eleanor McGee, Miranda Pallan, Yongzhong Sun, Myles Young, Philip Morgan   +16 more
doaj   +1 more source

Glassy materials investigated for nuclear reactor applications [PDF]

, 1968
Studies determine the feasibility of preparing fuel-bearing glasses and glasses bearing neutron-absorbing materials for use as crystalline fuel and control rods for reactors. Properties investigated were devitrification resistance, urania solubility, and
Lynch, E. D.
core   +1 more source