Results 91 to 100 of about 163,630 (295)
Study on phase transition phenomena in network traffic anomalies
Tongxin xuebao, 2006 Based on the theory of phase transition phenomena,the hypostases of network traffic anomalies with jam were researched.A new congestion mitigating mechanism with motional feedback of Hurst parameter was presented.Technical analysis and analog simulation ...
WANG Xin 1, DING Li 2
doaj +2 more sources
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
A feasible direction interior point algorithm for general nonlinear semidefinite programming [PDF]
, 2015 This paper deals with nonlinear smooth optimization problems with equality and inequality constraints , as well as semidefinite constraints on symmetric matrix-valued functions.
Bazán, Elmer +2 more
core
Finding Second-Order Stationary Points in Constrained Minimization: A Feasible Direction Approach [PDF]
This paper introduces a method for computing points satisfying the second-order necessary optimality conditions for nonconvex minimization problems subject to a closed and convex constraint set. The method comprises two independent steps corresponding to
Teboulle, Marc, Hallak, Nadav
core +1 more source
A Method of Solving Dynamic Character of High-Speed Angular-Contact Ball Bearing in Matrix Form
工程科学与技术, 2009 :The high-speed angular cantact ball bearing under load at three direction is used widespread in industry, and the analysis of it’s dynamic character is the base of bearing design and research of spool system.
zhaochunjiang, 葛世东, 王建梅
doaj
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
An active set feasible method for large-scale minimization problems with bound constraints [PDF]
, 2012 We are concerned with the solution of the bound constrained minimization problem {minf(x), la parts per thousand currency signxa parts per thousand currency signu}. For the solution of this problem we propose an active set method that combines ideas from
DE SANTIS, MARIANNA +2 more
core +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source