Results 81 to 90 of about 163,630 (295)

On the convergence of an alternating direction penalty method for nonconvex problems [PDF]

open access: yes, 2014
This paper investigates convergence properties ofscalable algorithms for nonconvex and structured optimization.We consider a method that is adapted from the classic quadraticpenalty function method, the Alternating Direction PenaltyMethod (ADPM).
C. Fischione   +7 more
core   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

open access: yesFEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile   +8 more
wiley   +1 more source

A Novel Direction-of-Arrival Estimation via Phase Retrieval with Unknown Sensor Gain-and-Phase Errors

open access: yesSensors, 2019
In signal array processing, high-resolution direction-of-arrival (DOA) estimation algorithms work well on the assumption that the system models are perfect. However, in practicality, there are imperfect system models in which sensor gain-and-phase errors
Lingwen Zhang   +3 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

A simple feasible SQP algorithm for inequality constrained optimization [PDF]

open access: yes, 2006
In this paper, an SQP method generating feasible iterates is presented to solve the nonlinear inequality constrained optimization problems. A new modified method which ensures the global and superlinear convergence is proposed by solving systems of ...
朱志斌, Zhu, Zhibin
core  

A HETEROGENEOUS ALTERNATING-DIRECTION METHOD FOR A MICRO-MACRO DILUTE POLYMERIC FLUID MODEL [PDF]

open access: yes, 2009
We examine a heterogeneous alternating-direction method for the approximate solution of the FENE Fokker-Planck equation from polymer fluid dynamics and we use this method to solve a coupled (macro-micro) Navier-Stokes-Fokker-Planck system for dilute ...
David J. Knezevic   +5 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Laminate circular cylindrical shell

open access: yesMATEC Web of Conferences, 2017
The paper deals with a numerical approach of optimal design modelling of laminate circular cylindrical shell. For thin-walled shells the classical shell theory is capable of accurately predicting the shell behaviour.
Kormaníková Eva, Kotrasová Kamila
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

A computer code for solving medium sized non-linear programming problems by the method of feasible directions. [PDF]

open access: yes, 1974
A computer code, FEASBL, is developed to maximize a non-linear objective function over a convex feasible region. The feasible region is defined by a set of non-linear and linear constraints on the variables.
Harrison, James Douglas.
core  

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