Results 21 to 30 of about 10,970 (177)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Decomposing complementizers: the fseq of French, Modern Greek, Serbo-Croatian and Bulgarian complementizers [PDF]

, 2018
This chapter discusses the morphosyntax of French, Modern Greek, Serbo-Croatian, and Bulgarian complementizers equivalent to English that. From long-distance wh-extractions across complementizers in these languages, it is shown that (i) the morpheme ...
Baunaz, Lena
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

DOM and a-topics

Isogloss
This study aims to investigate the extent to which language contact between Italian and Sicilian dialects has facilitated the integration of Differential Object Marking in the Sicilian regional variety of Italian, as compared to the Tuscan variety ...
Federica Interlandi
doaj   +1 more source

Configural and featural information in facial-composite images [PDF]

, 2014
Eyewitnesses are often invited to construct a facial composite, an image created of the person they saw commit a crime that is used by law enforcement to locate criminal suspects.
Kearley, Kevin, Fields, Stephen, Cristina Fodarella, Greenwood, Leah, Faye Skelton, Marsh, John Everett, John E. Marsh, Skelton, Faye, Peter J.B. Hancock, McIntyre, Alex H, Leah Greenwood, Fodarella, Cristina, Date, Louisa, Rachel Thorley, Khan, Humaira, Hancock, Peter J.B., Steve Fields, Hancock, Peter J B, Marsh, John E., Frowd, Charlie D, McIntyre, Alex, Thorley, Rachel, Greenwood, Leah Charlotte, Jones, Sharrome, Laura Nelson, Skelton, Faye Collette, Nelson, Laura, Frowd, Charlie D., Alex H. McIntyre, Hancock, Peter J.B. Hancock, Sharrome Jones, Marsh, John, Anna Williams, McIntyre, Alex H., Fields, Steve, Charlie D. Frowd, Frowd, Charlie, Louisa Date, Williams, Anna, Kevin Kearley   +39 more
core   +1 more source

‘Again’ separation in Italian [PDF]

, 2023
In Italian, ri- ‘again’ can be separated from the constituent it is semantically attached to and challenges the structural account for the ambiguity of ‘again’-type elements.
Liu, Yuyang, Yuyang Liu
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Minimality effects in agrammatic comprehension: The role of lexical restriction and feature impoverishment [PDF]

, 2014
Cross-linguistic studies in agrammatic aphasia have attested asymmetries in the comprehension of semantically reversible structures with canonical vs. non-canonical argument order, with the latter compromised.
Nerantzini, M., Bastiaanse, R., Varlokosta, S., Papadopoulou, D., Beretta, A.   +4 more
core   +2 more sources

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source