Results 51 to 60 of about 6,466,227 (249)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Evolutionary Feature Engineering Meets AutoML: A Feature-Efficient Framework for Malware Detection
IEEE AccessThe rapid evolution of malicious software continues to challenge modern cybersecurity systems, driven by increasingly sophisticated evasion techniques such as polymorphism, packing, and code obfuscation.
Muhammad Mohsin Raza +5 more
doaj +1 more source
Research on the Fault Coefficient in Complex Electrical Engineering
Applied Sciences, 2015 Fault detection and isolation in a complex system are research hotspots and frontier problems in the reliability engineering field. Fault identification can be regarded as a procedure of excavating key characteristics from massive failure data, then ...
Yi Sun, Yagang Zhang, Yinding Wang
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Feature engineering of environmental covariates improves plant genomic-enabled prediction
Frontiers in Plant ScienceIntroductionBecause Genomic selection (GS) is a predictive methodology, it needs to guarantee high-prediction accuracies for practical implementations.
Osval A. Montesinos-López +14 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
IEEE AccessThe integration of machine learning within educational environments has positioned learning analytics as a valuable approach for enhancing teaching and learning outcomes.
Dino Vlahek +2 more
doaj +1 more source
Feature engineering for sentiment analysis in e-health forums.
PLoS ONE, 2018 IntroductionExploiting information in health-related social media services is of great interest for patients, researchers and medical companies. The challenge is, however, to provide easy, quick and relevant access to the vast amount of information that ...
Jorge Carrillo-de-Albornoz +2 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source