Results 71 to 80 of about 6,466,227 (249)

Explainable Feature Engineering for Multi-class Money Laundering Classification [PDF]

Informatică economică
This paper provides insight into typical money laundering typologies used in the financial crime domain and provides a concrete set of methods through the use of which fraudulent transactions may be classified using traditional machine learning ...
Petre-Cornel GRIGORESCU, Antoaneta AMZA
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Towards Feature-Oriented Specification and Development with Event-B

, 2007
A proposal is made for the development of a feature-oriented reuse capability for safety-critical software construction using rigorous methods. We pr´ecis the Event-B language - the evolution of the B-Method of J.-R.
Poppleton, Michael
core   +1 more source

Web-based graphical user interface for automated materials feature engineering for machine learning

Science and Technology of Advanced Materials: Methods
Designing descriptors for materials and catalysts within machine learning is a complex process. In particular, material compositions can be represented using information from the periodic table. Additionally, feature engineering and feature selection add
Yoshiki Hasukawa, Mikael Kuwahara, Fernando Garcia-Escobar, Lauren Takahashi, Toshiaki Taniike, Keisuke Takahashi   +5 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Feature-based detection of breast cancer using convolutional neural network and feature engineering

Scientific Reports
Breast cancer (BC) is a prominent cause of female mortality on a global scale. Recently, there has been growing interest in utilizing blood and tissue-based biomarkers to detect and diagnose BC, as this method offers a non-invasive approach.
Hiba Allah Essa, Ebrahim Ismaiel, Mhd Firas Al Hinnawi   +2 more
doaj   +1 more source

Special Issue “Feature Review Papers in Mechanical Engineering”

Applied Sciences
The study and advancement of crank-slide actuating mechanisms based on four-link structural groups are promising for the development of new designs of crank presses and other stamping and forging machines [...]
Paolo Renna, Michele Ambrico
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source