Results 61 to 70 of about 461,060 (258)
The integration of machine learning within educational environments has positioned learning analytics as a valuable approach for enhancing teaching and learning outcomes.
Dino Vlahek +2 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Comparative Study of Feature Engineering Techniques for Predictive Data Analytics
In the rapidly evolving era of big data, predictive analytics has become a crucial approach in supporting data-driven decision-making across various sectors such as finance, healthcare, and marketing.
Lukman Santoso, Priyadi
doaj +1 more source
Feature engineering for sentiment analysis in e-health forums.
IntroductionExploiting information in health-related social media services is of great interest for patients, researchers and medical companies. The challenge is, however, to provide easy, quick and relevant access to the vast amount of information that ...
Jorge Carrillo-de-Albornoz +2 more
doaj +1 more source
Feature Engineering for Mid-Price Prediction With Deep Learning
Mid-price movement prediction based on the limit order book data is a challenging task due to the complexity and dynamics of the limit order book. So far, there have been very limited attempts for extracting relevant features based on the limit order ...
Adamantios Ntakaris +4 more
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Explainable Feature Engineering for Multi-class Money Laundering Classification [PDF]
This paper provides insight into typical money laundering typologies used in the financial crime domain and provides a concrete set of methods through the use of which fraudulent transactions may be classified using traditional machine learning ...
Petre-Cornel GRIGORESCU, Antoaneta AMZA
doaj +1 more source

