Results 61 to 70 of about 2,151,311 (285)

Assessing the Complexity of a Recovered Design and its Potential Redesign Alternatives [PDF]

open access: yes, 2009
Organised by: Cranfield UniversityReverse engineering techniques are applied to generate a part model where there is no existing documentation or it is no longer up to date.
ElMaraghy, W. H., Urbanic, R. J.
core  

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Feature engineering of environmental covariates improves plant genomic-enabled prediction

open access: yesFrontiers in Plant Science
IntroductionBecause Genomic selection (GS) is a predictive methodology, it needs to guarantee high-prediction accuracies for practical implementations.
Osval A. Montesinos-López   +14 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Learning From the Features We Ignore: A Critical Perspective on Feature Engineering and the Role of Feature Learning in Learning Analytics

open access: yesIEEE Access
The integration of machine learning within educational environments has positioned learning analytics as a valuable approach for enhancing teaching and learning outcomes.
Dino Vlahek   +2 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Threat Vector–Hierarchical Attack Representation Model-Based Threat Modeling and Security Assessment for Satellite Networks

open access: yesApplied Sciences
The rapid expansion of satellite networks has enabled the widespread deployment of satellite-based services across various sectors. However, these networks often prioritize cost-effectiveness over security considerations, leading to inherent ...
Junbeom Park   +5 more
doaj   +1 more source

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