Results 121 to 130 of about 949,168 (327)
Image Processing and Feature Extraction for Hull Structure GMAW Based on Weld Pool Visual Sensing [PDF]
, 2023 Ziquan Jiao +7 more
openalex +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
A Neoteric Feature Extraction Technique to Predict the Survival of Gastric Cancer Patients
DiagnosticsBackground: At the time of cancer diagnosis, it is crucial to accurately classify malignant gastric tumors and the possibility that patients will survive. Objective: This study aims to investigate the feasibility of identifying and applying a new feature
Warid Islam +6 more
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Low-voltage AC series arc fault detection based on Fisher-mutual information feature selection
International Journal of Metrology and Quality EngineeringThe detection of multi-feature fusion is a crucial approach to address the issue of series arc fault detection. Effective feature selection plays a vital role in enhancing the accuracy of the classifier and reducing system complexity.
Qin Baichuan +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
A Robust Rerank Approach for Feature Selection and Its Application to Pooling-Based GWA Studies [PDF]
, 2013 Jia‐Rou Liu, Po‐Hsiu Kuo, Hung Hung
openalex +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
MathematicsMany image-to-image translation tasks face an inherent problem of asymmetry in the domains, meaning that one of the domains is scarce—i.e., it contains significantly less available training data in comparison to the other domain.
Lidija Krstanović +4 more
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source