Results 71 to 80 of about 195,131 (299)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
ICA based feature learning and feature selection
, 2017 © 2016 IEEE. Feature extraction is playing a major role in bio signal processing. Feature identification and selection has two approaches. The common approach is engineering handcraft which is based on user experience and application area.
Al-Jumaily, AA, Ibrahim, MFI
core +1 more source
En marge de l’avant-garde américaine : le groupe Pool [PDF]
, 2008 En marge de l’avant-garde américaine : le groupe PoolLa poétesse américaine H.D. et la romancière anglaise Bryher, faisant ménage commun, rencontrent Kenneth Macpherson en 1926, par l’entremise de Frances Gregg (compagne de H.D. au début des années 1910).
Bovier, François
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Identification of special features in the electrolysiscavitation water treatment in pools
Eastern-European Journal of Enterprise Technologies, 2019 We developed an innovative technology of electrolysis-cavitation water purification and water treatment in pools. This method belongs to the group of physical water purification methods and its advantage is the absence of the need for costly chemical disinfectants and a degree of water purification from biological and organic pollutants of up to 97–98 %
Liliya Shevchuk +4 more
openaire +4 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Multiscale Feature Learning Based on Enhanced Feature Pyramid for Vehicle Detection
, 2021 Vehicle detection is a crucial task in autonomous driving systems. Due to large variance of scales and heavy occlusion of vehicle in an image, this task is still a challenging problem. Recent vehicle detection methods typically exploit feature pyramid to
Hoanh Nguyen
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Strengthening the Effectiveness of Pedestrian Detection with Spatially Pooled Features [PDF]
, 2014 16 pages. Appearing in Proc. European Conf.
Sakrapee Paisitkriangkrai +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source