Results 71 to 80 of about 88,907 (241)

An Experimental Comparison of Feature-Selection and Classification Methods for Microarray Datasets

Information, 2019
In the last decade, there has been a growing scientific interest in the analysis of DNA microarray datasets, which have been widely used in basic and translational cancer research.
Nicole Dalia Cilia, Claudio De Stefano, Francesco Fontanella, Stefano Raimondo, Alessandra Scotto di Freca   +4 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Compressive Sampling and Feature Ranking Framework for Bearing Fault Classification With Vibration Signals

IEEE Access, 2018
Failures of rolling element bearings are amongst the main causes of machines breakdowns. To prevent such breakdowns, bearing health monitoring is performed by collecting data from rotating machines, extracting features from the collected data, and ...
Hosameldin Ahmed, Asoke K. Nandi
doaj   +1 more source

matFR: a MATLAB toolbox for feature ranking

Bioinformatics, 2020
Abstract Summary Nowadays, it is feasible to collect massive features for quantitative representation and precision medicine, and thus, automatic ranking to figure out the most informative and discriminative ones becomes increasingly important.
Zhicheng Zhang, Xiaokun Liang, Wenjian Qin, Shaode Yu, Yaoqin Xie   +4 more
openaire   +2 more sources

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

ECG Feature Importance Rankings: Cardiologists Vs. Algorithms

IEEE Journal of Biomedical and Health Informatics
Feature importance methods promise to provide a ranking of features according to importance for a given classification task. A wide range of methods exist but their rankings often disagree and they are inherently difficult to evaluate due to a lack of ground truth beyond synthetic datasets. In this work, we put feature importance methods to the test on
Temesgen Mehari, Ashish Sundar, Alen Bosnjakovic, Peter Harris, Steven E. Williams, Axel Loewe, Olaf Doessel, Claudia Nagel, Nils Strodthoff, Philip J. Aston   +9 more
openaire   +6 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Energy Conservation in Wireless Sensor Networks Using Partly-Informed Sparse Autoencoder

IEEE Access, 2019
The energy in wireless sensor networks is considered a scarce commodity, especially in scenarios where it is difficult or impossible to provide supplementary energy sources once the initially available energy is used up.
Babajide O. Ayinde, Abdulaziz Y. Barnawi
doaj   +1 more source

Feature Ranking in Sentiment Analysis

International Journal of Computer Applications, 2014
With the rapid expansion of e-commerce over the past 15 years, more products are sold on the Web. More and more people are buying products online. In order to enhance customer shopping experience, it has become a common practice for online merchants to enable their customers to write reviews on products that they have purchased.
Seema Kolkur, Maryam K.Jawadwala
openaire   +1 more source