Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Suppression of natural convection heat transfer coefficients in an attic shaped enclosure [PDF]
, 2010 The use of convection suppression devices has been widely discussed in the literature as a means of reducing natural convection heat loss from enclosed spaces.
Carson, James K. +5 more
core +1 more source
Deep Multi-Feature Transfer Network for Fourier Ptychographic Microscopy Imaging Reconstruction. [PDF]
Sensors (Basel), 2022 Wang X +7 more
europepmc +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Mechanism and behavior of nucleate boiling heat transfer to the alkalai liquid metals [PDF]
, 1969 A model of boiling heat transfer to the alkali liquid metals is postulated from an examination of the events and phases of the nucleate boiling cycle. The model includes the important effect of microlayer evaporation which causes a wave of temperature ...
Deane, Charles William +1 more
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Fusion of Infrared and Visible Images Based on Three-Scale Decomposition and ResNet Feature Transfer. [PDF]
Entropy (Basel), 2022 Ji J +7 more
europepmc +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Investigation of a Sparse Autoencoder-Based Feature Transfer Learning Framework for Hydrogen Monitoring Using Microfluidic Olfaction Detectors. [PDF]
Sensors (Basel), 2022 Mirzaei H +5 more
europepmc +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Energy transfer, Dakota Access Pipeline Project
Energy T ransfer Dakota Access Pipeline Project August 20, 2014 ENERGY TRANSFER USAGE DAPL0071137Suggested Meeting Agenda Introduction of Attendees Project Description Iowa and Illinois Counties Being Crossed USACE Jurisdictional Boundaries/Buffers ...
Energy Transfer Partners, L.P.;
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