Results 61 to 70 of about 482,653 (299)

Untangling locality and orientation constraints in the L2 acquisition of anaphoric binding: a feature-based approach

open access: yes, 2012
This study offers a Minimalist analysis of the L2 acquisition of binding properties whereby cross-linguistic differences arise from the interaction of anaphoric feature specifications and operations of the computational system (Reuland 2001, 2011; Hicks ...
Dominguez, Laura   +2 more
core   +1 more source

PLS Subspace-Based Calibration Transfer for Near-Infrared Spectroscopy Quantitative Analysis

open access: yesMolecules, 2019
In order to enable the calibration model to be effectively transferred among multiple instruments and correct the differences between the spectra measured by different instruments, a new feature transfer model based on partial least squares regression ...
Yuhui Zhao   +5 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Towards Understanding Transfer Learning Algorithms Using Meta Transfer Features [PDF]

open access: yes, 2020
Transfer learning, which aims to reuse knowledge in different domains, has achieved great success in many scenarios via minimizing domain discrepancy and enhancing feature discriminability. However, there are seldom practical determination methods for measuring the transferability among domains.
Xin-Chun Li   +5 more
openaire   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

AST+SVMNet: A Novel Decomposition Method for Micro-Expression Recognition Based on Fusion Attention and Improved Spatio- Temporal Convolution by Feature Transfer

open access: yesIEEE Access
Micro-expression (ME) is spontaneous, rapid, and subtle facial mechanism that can reveal the concealed emotions. However, the short duration, low motion intensity, and small dataset of MEs make the extraction and learning of features from ME samples more
Peiyun Xue   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Efficiency-Sensitive Feature Selection and Probabilistic Feature Transfer for Scenic Image Recomposition

open access: yesIEEE Access
In this research, we address the sophisticated task of reconstructing the semantic elements within complex scenes, a critical endeavor for a broad range of artificial intelligence (AI) applications.
Zhendong Du, Yu Yu
doaj   +1 more source

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