Results 91 to 100 of about 380 (105)

Febrile nonhemolytic transfusion reactions to platelets

Current Opinion in Hematology, 1995
Although febrile nonhemolytic transfusion reactions to erythrocytes and platelets are not life threatening, the clinical symptoms associated with them cause discomfort for the patient, result in the use of premedicative drugs, and utilize nursing and laboratory resources.
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Platelet transfusion reactions: Febrile nonhemolytic reaction or bacterial contamination? Diagnosis, detection, and current preventive modalities

Journal of Cardiothoracic and Vascular Anesthesia, 2000
IN 1994, APPROXIMATELY 500,000 patients in the United States underwent cardiac surgery employing cardiopulmonary bypass.1 Cardiopulmonary bypass is associated with deleterious effects on platelet number and function, leading to excessive bleeding in 5% to 25% of patients.2,3 About half of the 7 million units of platelets transfused annually in the ...
A D, Sharma, H P, Grocott
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Pathophysiology of febrile nonhemolytic transfusion reactions

Current Opinion in Hematology, 1999
Most febrile nonhemolytic transfusion reactions (FNHTR) to platelets are caused by cytokines that accumulate in the product during storage. There have been numerous studies that have demonstrated high concentrations of leukocyte- and platelet-derived cytokines in stored platelet products.
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An unusual febrile nonhemolytic reaction occurred after transfusion in a thalassemia major patient with asymptomatic Plasmodium falciparum infection

Transfusion, 2010
BACKGROUND: Febrile nonhemolytic transfusion reactions occur in 0.12% of transfusions, usually during transfusion or within 4 to 6 hours after transfusion and are not medically dangerous.CASE REPORT: A patient with thalassemia from Togo with asymptomatic malaria in which the infection became clinically manifest only after blood transfusion, mimicking a
C. Boschetti, M. D. Cappellini, M. Colombi, A. Villa, R. Grande, C. Vercellati, F. Radaelli, L. Caspani, A. Zanella   +8 more
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Clinical significance of white cell antibodies in febrile nonhemolytic transfusion reactions

Transfusion, 1990
Febrile nonhemolytic transfusion reactions (FNHTRs) are associated with white cell (WBC) antibodies. The purposes of this study were to determine the frequency of WBC antibodies, to associate the severity of reactions with antibody specificity, and to distinguish FNHTRs from infection and postoperative fever.
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The utility of ≤3‐day‐old whole‐blood platelets in reducing the incidence of febrile nonhemolytic transfusion reactions

Transfusion, 2000
BACKGROUND: Febrile nonhemolytic transfusion reactions (FNHTRs) to platelet transfusions have been linked to the presence of cytokines in supernatant plasma. Cytokine concentration is directly related to WBC content and storage time. This study evaluated the effect of limiting the storage time of random‐donor platelet concentrates on the FNHTR rate ...
D L, Kelley, J, Mangini, I, Lopez-Plaza, D J, Triulzi   +3 more
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The effect of prestorage WBC reduction on the rates of febrile nonhemolytic transfusion reactions to platelet concentrates and RBC

Transfusion, 2004
BACKGROUND:  Febrile non‐hemolytic transfusion reactions (FNHTRs) are a common complication of platelet concentrate (PC) and RBC transfusions, usually ascribed to cytokines released by WBCs and perhaps the platelets themselves during storage. Prestorage WBC reduction should abrogate the accumulation of these cytokines reducing the number of FNHTRs ...
Mark H, Yazer, Linda, Podlosky, Gwen, Clarke, Susan M, Nahirniak   +3 more
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Effects of Leukoreduction and Premedication With Acetaminophen and Diphenhydramine in Minimizing Febrile Nonhemolytic Transfusion Reactions and Allergic Transfusion Reactions During and After Blood Product Administration

Journal of Pediatric Oncology Nursing, 2014
Transfusion-related reactions cause unwanted interruptions in blood-product administration and potential complications for patients. The most common reactions are febrile nonhemolytic transfusion reactions (FNHTRs) and allergic transfusion reactions (ATRs).
Joana, Duran, Sulman, Siddique, Myra, Cleary   +2 more
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Clinical assessment of preventing febrile nonhemolytic transfusion reaction by leukocyte-depleted blood transfusion.

Zhongguo shi yan xue ye xue za zhi, 2003
The objective was designed to assess the clinical efficiency of preventing febrile nonhemolytic transfusion reactions (FNHTR) with transfusion of leukocyte-depleted RBC and platelet concentrates. One hundred patients with cirrhosis of liver, gastric ulcer and cancer were selected to receive RBC concentrates with leukocyte filtration.
Shu-Ming, Zhao, Xiao-Ling, Cheng, Jian, Hu, Guo-Chun, Xiang, Jia-Si, Zhang, Ru-Qing, Li   +5 more
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Universal Leukoreduction Decreases the Incidence of Febrile Nonhemolytic Transfusion Reactions to Cellular Blood Components: A 5 Year Study

International Blood Research & Reviews, 2014
Background: Febrile nonhemolytic transfusion reactions (FNHTRs) are common complications associated with allogenic transfusion and it is caused by the leucocytes and cytokines released by leucocytes during ...
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