Results 131 to 140 of about 2,279,418 (152)
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Transfusion, 2004
BACKGROUND: Febrile nonhemolytic transfusion reactions (FNHTR) is a relatively common complication associated with allogeneic transfusion. Because WBCs have been implicated in the mechanism of FNHTRs, it has been proposed that the transfusion of leukoreduced RBCs should be associated with a decreased incidence of FNHTRs.
Karen E King, Paul M Ness, R Sue Shirey
exaly +3 more sources
BACKGROUND: Febrile nonhemolytic transfusion reactions (FNHTR) is a relatively common complication associated with allogeneic transfusion. Because WBCs have been implicated in the mechanism of FNHTRs, it has been proposed that the transfusion of leukoreduced RBCs should be associated with a decreased incidence of FNHTRs.
Karen E King, Paul M Ness, R Sue Shirey
exaly +3 more sources
Transfusion, 1962
In more than ten thousand transfusions given over a four‐year period to 1,649 patients, the incidence of urticarial reactions was 1.1 per cent. There were no hemolytic transfusion reactions and none due to bacterial contamination or to bacterial pyrogens.
Paul J Schmidt, M H McGinniss, S V Kevy
exaly +3 more sources
In more than ten thousand transfusions given over a four‐year period to 1,649 patients, the incidence of urticarial reactions was 1.1 per cent. There were no hemolytic transfusion reactions and none due to bacterial contamination or to bacterial pyrogens.
Paul J Schmidt, M H McGinniss, S V Kevy
exaly +3 more sources
Transfusion and Apheresis Science, 2008
Accumulated inflammatory cytokines are considered to be a cause of febrile nonhemolytic transfusion reactions (FNHTRs) of platelet transfusions. Inflammatory cytokines have been found in red cell components stored at 4 degrees C; however, their relationship to FNHTRs has not been clearly demonstrated following red cell transfusions.
Tetsunori Tasaki, Yasutaka Hoshi
exaly +3 more sources
Accumulated inflammatory cytokines are considered to be a cause of febrile nonhemolytic transfusion reactions (FNHTRs) of platelet transfusions. Inflammatory cytokines have been found in red cell components stored at 4 degrees C; however, their relationship to FNHTRs has not been clearly demonstrated following red cell transfusions.
Tetsunori Tasaki, Yasutaka Hoshi
exaly +3 more sources
Transfusion, 2000
BACKGROUND: Febrile nonhemolytic transfusion reactions (FNHTRs) to platelet transfusions have been linked to the presence of cytokines in supernatant plasma. Cytokine concentration is directly related to WBC content and storage time. This study evaluated the effect of limiting the storage time of random‐donor platelet concentrates on the FNHTR rate ...
D L, Kelley +3 more
exaly +3 more sources
BACKGROUND: Febrile nonhemolytic transfusion reactions (FNHTRs) to platelet transfusions have been linked to the presence of cytokines in supernatant plasma. Cytokine concentration is directly related to WBC content and storage time. This study evaluated the effect of limiting the storage time of random‐donor platelet concentrates on the FNHTR rate ...
D L, Kelley +3 more
exaly +3 more sources
Transfusion, 2004
BACKGROUND: Febrile non‐hemolytic transfusion reactions (FNHTRs) are a common complication of platelet concentrate (PC) and RBC transfusions, usually ascribed to cytokines released by WBCs and perhaps the platelets themselves during storage. Prestorage WBC reduction should abrogate the accumulation of these cytokines reducing the number of FNHTRs ...
Mark Yazer, Gwen Clarke, Susan Nahirniak
exaly +3 more sources
BACKGROUND: Febrile non‐hemolytic transfusion reactions (FNHTRs) are a common complication of platelet concentrate (PC) and RBC transfusions, usually ascribed to cytokines released by WBCs and perhaps the platelets themselves during storage. Prestorage WBC reduction should abrogate the accumulation of these cytokines reducing the number of FNHTRs ...
Mark Yazer, Gwen Clarke, Susan Nahirniak
exaly +3 more sources
Clinical significance of white cell antibodies in febrile nonhemolytic transfusion reactions
Transfusion, 1990Febrile nonhemolytic transfusion reactions (FNHTRs) are associated with white cell (WBC) antibodies. The purposes of this study were to determine the frequency of WBC antibodies, to associate the severity of reactions with antibody specificity, and to distinguish FNHTRs from infection and postoperative fever.
exaly +3 more sources
Febrile Nonhemolytic Transfusion Reactions
Clinical Journal of Oncology Nursing, 2002A. FNHTRs are reported in 0.5%–5% of all transfusions. B. FNHTRs are the most common complication of platelet transfusion. 1. Incidence ranges from 1.7% to 31%. 2. Higher incidences are seen in patients who have received multiple prior transfusions. C. Incidence may decrease with increased use of prestorage leukocytereduced blood products. D.
openaire +2 more sources
Journal of Cardiothoracic and Vascular Anesthesia, 2000
IN 1994, APPROXIMATELY 500,000 patients in the United States underwent cardiac surgery employing cardiopulmonary bypass.1 Cardiopulmonary bypass is associated with deleterious effects on platelet number and function, leading to excessive bleeding in 5% to 25% of patients.2,3 About half of the 7 million units of platelets transfused annually in the ...
A D, Sharma, H P, Grocott
openaire +2 more sources
IN 1994, APPROXIMATELY 500,000 patients in the United States underwent cardiac surgery employing cardiopulmonary bypass.1 Cardiopulmonary bypass is associated with deleterious effects on platelet number and function, leading to excessive bleeding in 5% to 25% of patients.2,3 About half of the 7 million units of platelets transfused annually in the ...
A D, Sharma, H P, Grocott
openaire +2 more sources