Results 91 to 100 of about 8,165 (189)

The last defence? Surgical aspects of gouty arthritis of hand and wrist [PDF]

open access: yes, 2011
OBJECTIVE: To review the epidemiology, pathophysiology, clinical manifestations, diagnosis, and treatment of gouty arthritis of the hand and wrist, with a focus on the surgical aspects. DATA SOURCES AND EXTRACTION: Electronic databases including MEDLINE,
Fung, BKK, Tang, CKY
core  

Gout – a treatable condition [PDF]

open access: yes, 2018
To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked FilesÞvagsýrugigt er liðbólgusjúkdómur sem í flestum tilfellum er læknanlegur en ...
Björn Guðbjörnsson   +3 more
core   +1 more source

Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney. [PDF]

open access: yes, 2016
BackgroundExcess body burden of uric acid promotes gout. Diminished renal clearance of uric acid causes hyperuricemia in most patients with gout, and the renal urate transporter (URAT)1 is important for regulation of serum uric acid (sUA) levels.
Girardet, Jean-Luc   +12 more
core   +2 more sources

Коморбідність, серцево-судинна патологія і лікування гіперурикемії – чи запобігає захворюванню алопуринол? (огляд літератури) [PDF]

open access: yes, 2016
Огляд літератури присвячено проблемам коморбідності за поєднання серцево-судинних захворювань і гіперурикемії в співвідношенні з клінічними проявами ...
Аль Салама, Мухамед Васек Обейд   +1 more
core  

Sintesis, penilaian biologi dan kajian dok sebatian auron ke atas enzim xantin oksidase [PDF]

open access: yes, 2018
Perencatan aktiviti xantin oksidase (XO) merupakan satu pendekatan terapeutik yang berkesan dalam rawatan penyakit seperti gout dan hiperurikemia. Selain itu, penggunaan perencat XO juga dapat diluaskan kepada rawatan kecederaan contohnya reperfusi ...
Ang, Serene   +4 more
core  

Efficacy and safety of febuxostat in elderly female patients

open access: yesClinical Interventions in Aging, 2014
Tomohiro Mizuno,1,2 Takahiro Hayashi,3 Sayo Hikosaka,1 Yuka Shimabukuro,1 Maho Murase,1 Kazuo Takahashi,2 Hiroki Hayashi,2 Yukio Yuzawa,2 Tadashi Nagamatsu,1 Shigeki Yamada3 1Department of Analytical Pharmacology, Graduate School of Pharmacy, Meijo ...
Mizuno T   +9 more
doaj  

Febuxostat efficiently reduces the progression of chronic kidney disease in asymptomatic hyperuricemia: an interventional study

open access: yesThe Egyptian Journal of Internal Medicine
Background Therapeutic approaches for addressing asymptomatic chronic kidney disease (CKD) with renal impairment requires careful consideration, as there is a lack of substantial evidence endorsing specific medications.
Showkat Azad   +13 more
doaj   +1 more source

Neue Erkenntnisse zur Pathophysiologie und Therapie der Gicht [PDF]

open access: yes, 2018
Zusammenfassung: Gicht wird durch die Ablagerung von Mononatriumurat- (MNU-)Kristallen im Gewebe verursacht, durch die eine lokale Entzündungsreaktion ausgelöst wird. Bei älteren Menschen ist sie die häufigste entzündliche Gelenkerkrankung.
So, A.
core  

Comparative efficacy and safety of febuxostat and allopurinol in chronic kidney disease stage 3–5 patients with asymptomatic hyperuricemia: a network meta-analysis

open access: yesRenal Failure
Objective This study evaluates and compares the effectiveness and safety of febuxostat and allopurinol in chronic kidney disease (CKD) stages 3–5 patients with asymptomatic hyperuricemia using a network meta-analysis.Methods A systematic review and ...
Jiaojiao Chen   +3 more
doaj   +1 more source

Xanthine oxidoreductase inhibition ameliorates high glucose-induced glomerular endothelial injury by activating AMPK through the purine salvage pathway

open access: yesScientific Reports
Xanthine oxidoreductase (XOR) contributes to reactive oxygen species production. We investigated the cytoprotective mechanisms of XOR inhibition against high glucose (HG)-induced glomerular endothelial injury, which involves activation of the AMP ...
Keum-Jin Yang   +5 more
doaj   +1 more source

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