Results 91 to 100 of about 8,165 (189)
The last defence? Surgical aspects of gouty arthritis of hand and wrist [PDF]
OBJECTIVE: To review the epidemiology, pathophysiology, clinical manifestations, diagnosis, and treatment of gouty arthritis of the hand and wrist, with a focus on the surgical aspects. DATA SOURCES AND EXTRACTION: Electronic databases including MEDLINE,
Fung, BKK, Tang, CKY
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Gout – a treatable condition [PDF]
To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked FilesÞvagsýrugigt er liðbólgusjúkdómur sem í flestum tilfellum er læknanlegur en ...
Björn Guðbjörnsson +3 more
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Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney. [PDF]
BackgroundExcess body burden of uric acid promotes gout. Diminished renal clearance of uric acid causes hyperuricemia in most patients with gout, and the renal urate transporter (URAT)1 is important for regulation of serum uric acid (sUA) levels.
Girardet, Jean-Luc +12 more
core +2 more sources
Коморбідність, серцево-судинна патологія і лікування гіперурикемії – чи запобігає захворюванню алопуринол? (огляд літератури) [PDF]
Огляд літератури присвячено проблемам коморбідності за поєднання серцево-судинних захворювань і гіперурикемії в співвідношенні з клінічними проявами ...
Аль Салама, Мухамед Васек Обейд +1 more
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Sintesis, penilaian biologi dan kajian dok sebatian auron ke atas enzim xantin oksidase [PDF]
Perencatan aktiviti xantin oksidase (XO) merupakan satu pendekatan terapeutik yang berkesan dalam rawatan penyakit seperti gout dan hiperurikemia. Selain itu, penggunaan perencat XO juga dapat diluaskan kepada rawatan kecederaan contohnya reperfusi ...
Ang, Serene +4 more
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Efficacy and safety of febuxostat in elderly female patients
Tomohiro Mizuno,1,2 Takahiro Hayashi,3 Sayo Hikosaka,1 Yuka Shimabukuro,1 Maho Murase,1 Kazuo Takahashi,2 Hiroki Hayashi,2 Yukio Yuzawa,2 Tadashi Nagamatsu,1 Shigeki Yamada3 1Department of Analytical Pharmacology, Graduate School of Pharmacy, Meijo ...
Mizuno T +9 more
doaj
Background Therapeutic approaches for addressing asymptomatic chronic kidney disease (CKD) with renal impairment requires careful consideration, as there is a lack of substantial evidence endorsing specific medications.
Showkat Azad +13 more
doaj +1 more source
Neue Erkenntnisse zur Pathophysiologie und Therapie der Gicht [PDF]
Zusammenfassung: Gicht wird durch die Ablagerung von Mononatriumurat- (MNU-)Kristallen im Gewebe verursacht, durch die eine lokale Entzündungsreaktion ausgelöst wird. Bei älteren Menschen ist sie die häufigste entzündliche Gelenkerkrankung.
So, A.
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Objective This study evaluates and compares the effectiveness and safety of febuxostat and allopurinol in chronic kidney disease (CKD) stages 3–5 patients with asymptomatic hyperuricemia using a network meta-analysis.Methods A systematic review and ...
Jiaojiao Chen +3 more
doaj +1 more source
Xanthine oxidoreductase (XOR) contributes to reactive oxygen species production. We investigated the cytoprotective mechanisms of XOR inhibition against high glucose (HG)-induced glomerular endothelial injury, which involves activation of the AMP ...
Keum-Jin Yang +5 more
doaj +1 more source

