Results 81 to 90 of about 6,049 (169)

Study on Ameliorative Effect of Febuxostat on Gout Induced Model in Broiler Chicks

open access: yes, 2017
This work was conducted on six groups of day-old Cobb-400 broiler chicks to study the ameliorative effect of febuxostat on gout induced model. Clinical signs were noticed in birds of diclofenac control group II and low dose febuxostat treated group IV ...
D. J. Dave   +4 more
core   +1 more source

Febuxostat improves outcome in a rat model of cancer cachexia

open access: yes, 2015
Background Activity of xanthine oxidase is induced in cancer cachexia, and its inhibition by allopurinol or oxypurinol improves survival and reduces wasting in the Yoshida hepatoma cancer cachexia model.
Springer, Jochen   +8 more
core   +1 more source

A pharmacokinetic‐pharmacodynamic study of a single dose of febuxostat in healthy subjects

open access: yes, 2020
Aims To examine the pharmacokinetic‐phamacodynamic (PK‐PD) relationships of plasma febuxostat and serum urate and the effect of a single dose of the drug on renal excretion and fractional clearance of urate (FCU).
Sophie L. Stocker   +15 more
core   +1 more source

The future of febuxostat after the Cardiovascular Safety of Febuxostat and Allopurinol in Patients with Gout and Cardiovascular Morbidities (CARES) trial: who CARES?

open access: yes, 2018
We readwith interest the review by Robinson et al. [1] on the role of febuxostat in the treatment of hyperuricemia. The authors discuss data from phase II and III clinical trials on the efficacy and safety of febuxostat as well as from randomized ...
Katsiki, Niki, Borghi, Claudio
core   +1 more source

The Urate-lowering Efficacy and Safety of Febuxostat in Korean Patients with Gout [PDF]

open access: yes, 2013
Objective: To compare the urate-lowering efficacy and the safety of febuxostat, allopurinol and placebo in Korean patients with gout for 4 weeks. Methods: Subjects (n=182) with gout were randomized to febuxostat (40, 80, 120 mg), allopurinol 300 mg ...
이수곤
core   +1 more source

Enhancing Dissolution of Febuxostat: Novel Febuxostat–Syringic Acid Multicomponent Crystals via Liquid-Assisted Grinding

open access: yes
Gout is a chronic inflammatory disease characterized by the deposition of monosodium urate crystals in the joints, and its global prevalence continues to increase.
Gita Sri Fitri   +3 more
core   +1 more source

Contribution of Organic Anion Transporter 3 in Delayed Elimination of Methotrexate by Concomitant Administration of Febuxostat [PDF]

open access: yes
Ikemura K., Kobayashi S., Wang D., et al. Contribution of Organic Anion Transporter 3 in Delayed Elimination of Methotrexate by Concomitant Administration of Febuxostat.
Wang, Danni   +3 more
core   +1 more source

COMPARISON BETWEEN RENOPROTECTIVE EFFECTS OF FEBUXOSTAT AND ALLOPURINOL IN CHRONIC KIDNEY DISEASE PATIENTS WITH HYPERURICEMIA

open access: yes, 2023
Objective: The objective of the study was to compare the renoprotective effects of febuxostat versus allopurinol in chronic kidney disease patients with hyperuricemia.
matta, saksham   +5 more
core   +1 more source

The mass spectrometry (MS) parameters for assays of febuxostat.

open access: yes, 2016
The mass spectrometry (MS) parameters for assays of febuxostat.
Zhu Luo (1525882)   +5 more
core   +1 more source

Comparisons of Therapeutic Effects of Allopurinol and Febuxostat in Chronic Hemodialysis Patients [PDF]

open access: yes, 2019
More than few patients on maintenance hemodialysis present with hyperuricemia, and the control of serum uric acid level is an important issue in the long-term management.
Murayama, Yoshiki   +6 more
core   +1 more source

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