Results 61 to 70 of about 8,165 (189)

Cardiovascular Safety of Febuxostat and Allopurinol in Hyperuricemic Patients With or Without Gout: A Network Meta-Analysis

Frontiers in Medicine, 2021
Background: Hyperuricemia is a common metabolic disease and has become a public health problem because of its increasing prevalence and association with comorbidities.
Shengzhao Zhang, Shengzhao Zhang, Ting Xu, Ting Xu, Qingyang Shi, Sheyu Li, Sheyu Li, Ling Wang, Zhenmei An, Na Su, Na Su   +10 more
doaj   +1 more source

Prevalence and possible causes of hypouricemia at a tertiary care hospital [PDF]

, 2016
Background/Aims: We aimed to investigate the prevalence and possible causes of hypouricemia in the Korean population and to compare our findings with published results of other populations.
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core   +4 more sources

African American patients with gout: efficacy and safety of febuxostat vs allopurinol

BMC Musculoskeletal Disorders, 2012
Background African Americans are twice as likely as Caucasians to develop gout, but they are less likely to be treated with urate-lowering therapy (ULT).
Wells Alvin F, MacDonald Patricia A, Chefo Solomon, Jackson Robert L   +3 more
doaj   +1 more source

Discordant American College of Physicians and international rheumatology guidelines for gout management: consensus statement of the Gout, Hyperuricemia and Crystal-Associated Disease Network (G-CAN). [PDF]

, 2017
In November 2016, the American College of Physicians (ACP) published a clinical practice guideline on the management of acute and recurrent gout. This guideline differs substantially from the latest guidelines generated by the American College of ...
A Chhana, A Qaseem, A Qaseem, AB Gutman, Alexander K. So, CF Kuo, CY Lam Erwin, D Khanna, D Khanna, DF Ransohoff, DH Solomon, DJ McCarty, DJ McCarty, DL Sackett, E Jutkowitz, E Pascual, F Lioté, F Perez-Ruiz, F Perez-Ruiz, F Perez-Ruiz, F Rees, F Sivera, Frédéric Lioté, H Park, HK Choi, HR Schumacher, HR Schumacher, HR Schumacher Jr., HS Baraf, Hyon K. Choi, J Li-Yu, JA Singh, JA Singh, JE Seegmiller, JN Loeb, JS Faires, JS Sundy, Kenneth G. Saag, KG Saag, Lisa K. Stamp, LK Stamp, M Doherty, MA Becker, MA Becker, MA Becker, MA Becker, Michael Doherty, N Bellamy, N Dalbeth, N Dalbeth, N Dalbeth, N Dalbeth, Nicola Dalbeth, O Aati, P Richette, P Richette, Pascal Richette, PC Robinson, PG Shekelle, PP Khanna, PS Hench, R Halpern, R Jackson, RM McLean, Robert Terkeltaub, SI Hung, SY Lim, T Bardin, T Neogi, Thomas Bardin, TM Ko, U Kiltz, V Strand   +72 more
core   +1 more source

Clinical and Histopathological Features of Oral Verruciform Xanthoma: A Case Series of Three Patients

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Oral verruciform xanthoma (OVX) is a rare benign lesion of the oral mucosa that often mimics other oral diseases. We report three cases of OVX and describe their clinical and histopathological characteristics. All patients presented with asymptomatic, well‐demarcated verrucous lesions located on the attached gingiva. The patients ranged in age
Taku Kimura, Ken‐ichiro Sakata, Keisuke Nakamura, Aya Yanagawa Matsuda, Kazuhiro Kawamura, Yusuke Nakamura   +5 more
wiley   +1 more source

The efficacy and safety of febuxostat for urate lowering in gout patients ≥65 years of age

BMC Geriatrics, 2012
Background The incidence of gout rises with increasing age. Management of elderly (≥65 years) gout patients can be challenging due to high rates of comorbidities, such as renal impairment and cardiovascular disease, and concomitant medication use ...
Jackson Robert L, Hunt Barbara, MacDonald Patricia A   +2 more
doaj   +1 more source

Revisiting the Ethics of Urate‐Lowering Therapy Clinical Trials for Gout Management

Arthritis &Rheumatology, EarlyView.
Lisa K. Stamp, Dien Ho, Nicola Dalbeth
wiley   +1 more source

Pleiotrophin-induced endothelial cell migration is regulated by xanthine oxidase-mediated generation of reactive oxygen species [PDF]

, 2015
Pleiotrophin (PTN) is a heparin-binding growth factor that induces cell migration through binding to its receptor protein tyrosine phosphatase beta/zeta (RPTPβ/ζ) and integrin alpha v beta 3 (ανβ3).
Abdulnour, Antoine, Bir, Bryan, Dhar-Mascareno, Dupont, Evangelia Papadimitriou, Goitre, Griguer, Güleç, Hatziapostolou, Hatziapostolou, Heissig, Heumüller, Holmström, Kalyanaraman, Kim, Kojima, Komaki, Kou, Koutsioumpa, Lange, Li, Linder, Lisanti, Lu, Margarita Lamprou, Maria Hatziapostolou, Mikelis, Naik, Nelly Kieffer, Nomura, Omori, Pantazaka, Papadimitriou, Polykratis, Polytarchou, Polytarchou, Polytarchou, Polytarchou, Prajda, Prajda, Ray, Romagnoli, Sabán-Ruiz, Samra, Schröder, Sies, Silver, Sotiria Tsirmoula, Terman, Tsirmoula, Ushio-Fukai, Wang, Wilkinson-Berka, Wind, Yokoi, Zhang   +57 more
core   +1 more source

Gout - a guide for the general and acute physicians. [PDF]

, 2017
Gout is the most prevalent inflammatory arthritis and affects 2.5% of the general population in the UK. It is also the only arthritis that has the potential to be cured with safe, inexpensive and well tolerated urate-lowering treatments, which reduce ...
Abhishek, A, Doherty, M, Roddy, E
core   +1 more source

Long‐Term Opioids in Gout: A Matched Cohort Study From the Veterans Health Administration

Arthritis Care &Research, Volume 78, Issue 3, Page 344-351, March 2026.
Objective Though used frequently to treat flare, risk of long‐term opioid exposure in gout has not been well defined. In this study, we examined the hypothesis that people with gout are more likely than individuals without gout to be prescribed long‐term opioids over time.
Lindsay N. Helget, Bryant R. England, Punyasha Roul, Harlan Sayles, Tuhina Neogi, James R. O'Dell, Joshua F. Baker, Ted R. Mikuls   +7 more
wiley   +1 more source