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Fecal Elastase 1 Determination in Chronic Pancreatitis
Digestive Diseases and Sciences, 1999This study assessed the diagnostic accuracy of fecal elastase 1 in chronic pancreatitis. Fifty-three healthy subjects, 44 patients with chronic pancreatitis (22 severe, 13 moderate, and 9 mild), and 43 patients with nonpancreatic digestive disease were studied.
Raffaele Pezzilli +2 more
exaly +3 more sources
Fecal elastase-1: Utility in pancreatic function in cystic fibrosis [PDF]
Journal of Cystic Fibrosis, 2006 Early detection and management of pancreatic insufficiency is essential to optimize health and outcomes in cystic fibrosis patients. The gold standard measures for assessment of pancreatic function are direct pancreatic stimulation tests, which have numerous limitations.
Ameet Daftary
exaly +3 more sources
A Novel Fecal Elastase Assay for the Detection of Pancreatic Exocrine Insufficiency
Clinical Laboratory, 2022Fecal pancreatic elastase 1 (FPE1) is an established screening test for pancreatic exocrine insufficiency (PEI), a condition that is underdiagnosed and if not treated may cause significant morbidity. The aim of this study was to compare a new FPE1 machine based CLIA kit to an ELISA assay which is considered the de facto gold standard in our laboratory ...
Yair, Huta +5 more
openaire +2 more sources
Impaired Fecal Elastase Excretion in Uremic Pancreopathy
Digestive Diseases and Sciences, 2000To evaluate pancreatic exocrine function in uremia, 25 patients undergoing regular hemodialysis without clinical evidence of pancreatic disease and 25 healthy control subjects were studied by fecal elastase 1 and chymotrypsin. Abdominal ultrasonography and measurement of serum lipase, calcium, phosphate, and parathormone were also carried out.
M, Ventrucci +7 more
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Pediatrics, 2002
Objective. Exocrine pancreatic function in patients with cystic fibrosis (CF) can be evaluated by direct and indirect tests. In pediatric patients, indirect tests are preferred because of their less invasive character, especially in CF patients with respiratory disease.
Jaroslaw Walkowiak
exaly +3 more sources
Objective. Exocrine pancreatic function in patients with cystic fibrosis (CF) can be evaluated by direct and indirect tests. In pediatric patients, indirect tests are preferred because of their less invasive character, especially in CF patients with respiratory disease.
Jaroslaw Walkowiak
exaly +3 more sources
Fecal Elastase-1 as a Test for Pancreatic Function: a Review
Clinical Chemistry and Laboratory Medicine, 2002Pancreatic elastase-1 is a specific human protease synthetized by the acinar cells. Immunoreactive elastase-1 cannot be detected in either porcine or bovine pancreatic enzyme preparations. It is very stable and, in contrast to fecal chymotrypsin, elastase is unaffected by exogenous pancreatic enzyme treatment, and correlates well with exocrine ...
Roberto, Dominici, Carlo, Franzini
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Effect of intestinal inflammation on fecal elastase concentration in dogs
Veterinary Clinical Pathology, 2005Background: A commercially available ELISA kit for fecal elastase measurement can be used in the diagnosis of exocrine pancreatic insufficiency (EPI) in dogs. However, other causes of diarrhea also may affect fecal elastase concentration. Objective: This study was undertaken to determine whether intestinal inflammation alters fecal elastase ...
Battersby, IA +4 more
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Low fecal elastase-1 in type I diabetes mellitus
Zeitschrift Fur Gastroenterologie, 2001Previous studies suggested impaired pancreatic exocrine function in type I diabetes patients, but have been limited by small or highly selected samples. Fecal elastase-1 has facilitated evaluation of pancreatic dysfunction in population-based studies.112 type I diabetic patients (age +/- SD: 37 +/- 11 years; 47 % males; diabetes duration: 12.5 +/- 10.5
A, Icks +3 more
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The role of fecal elastase-1 in detecting exocrine pancreatic disease
Nature Reviews Gastroenterology & Hepatology, 2011Exocrine pancreatic disease is thought to be uncommon in clinical practice and usually secondary to excess alcohol intake. Although excess alcohol intake does account for many cases of exocrine pancreatic disease, other conditions are associated with exocrine pancreatic insufficiency and such dysfunction perhaps occurs more frequently than ...
John S, Leeds +2 more
openaire +2 more sources