Results 101 to 110 of about 64,339 (308)

Cars2‐Mediated Cysteine Catabolism Drives Brown Fat Development and Thermogenesis Through Persulfidating EBF2

Advanced Science, EarlyView.
We demonstrate that Cars2, a cysteine catabolic enzyme in mouse iBAT, is critical for cold tolerance and brown adipocyte differentiation. Through its CPERS activity, Cars2 produces CysSSH/H2S to induce EBF2 persulfidation, promoting its interaction with PPARγ and BRG1 to enhance thermogenic gene expression.
Xin Peng, Hongyong Song, Yin Long, Kaimin Wu, Yinkun Fu, Wenkai Zhou, Wenyan Li, Zhe Shi, Xu‐Yun Zhao   +8 more
wiley   +1 more source

Meat processing and colon carcinogenesis: Cooked, nitrite-treated and oxidized high-heme cured meat promotes mucin depleted foci in rats [PDF]

, 2010
Processed meat intake is associated with colorectal cancer risk, but no experimental study supports the epidemiologic evidence. To study the effect of meat processing on carcinogenesis promotion, we first did a 14-day study with 16 models of cured meat ...
Caderni, Claude Genot, Cross, Cummings, Denis E. Corpet, Estevez, Fabrice H.F. Pierre, Françoise Guéraud, Jean-Luc Vendeuvre, Kälble, Lethuaut, Linseisen, Michelle Viau, Mirvish, Mirvish, Nathalie Naud, Parnaud, Pierre, Pierre, Pierre, Raphaëlle L. Santarelli, Sandhu, Sawa, Sesink, Shahidi, Sinha, Sylviane Taché   +26 more
core   +4 more sources

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

High pCO 2 levels affect metabolic rate, but not feeding behavior and fitness, of farmed giant mussel Choromytilus chorus [PDF]

, 2018
Indexación: Scopus.Acknowledgements. We thank Luisa Saavedra and Araceli Rodriguez-Romero for their help in the field and during laboratory activities. We also acknowledge Laura Ramajo for help with AT estimations.
Benítez, S., Duarte, C., Lagos, N.A., Lardies, M.A., Navarro, J.M., Opitz, T., Osores, S.   +6 more
core   +1 more source

Tracking of [14C]Polystyrene Nanoplastics in Pregnant Mice

Advanced Science, EarlyView.
This study investigates [14C]polystyrene nanoplastic ([14C]PS) translocation in late‐stage pregnant mice after intranasal (0.5 mg of [14C]PS on GD12, GD14, and GD16, n = 6) and intravenous administration (1.5 mg of [14C]PS on GD16, n = 6). 14C‐radiolabel allows quantitative tracking of unmodified polystyrene nanoplastics.
Olga Khaybullina, Pallavi Sarkhel, Outi M. Keinänen   +2 more
wiley   +1 more source

Digestion of Protein in Premature and Term Infants. [PDF]

, 2012
Premature birth rates and premature infant morbidity remain discouragingly high. Improving nourishment for these infants is the key for accelerating their development and decreasing disease risk. Dietary protein is essential for growth and development of
Dallas, David C, German, J Bruce, Underwood, Mark A, Zivkovic, Angela M   +3 more
core   +2 more sources

Excretion of Urine Mixed with Air and Fecal Material

The Korean Journal of Internal Medicine, 2011
A 19-year-old man visited our clinic with dysuria, pneumaturia, and fecal material in the urine. He had a 5-month history of recurrent cystitis. The abdomen was soft with mild suprapubic tenderness. Urinalysis revealed 25-30 white blood cells and 5-9 red blood cells per high-power field.
Lee, Sik, Lee, Soo Teik
openaire   +2 more sources

Construction of a MOF‐Based Snap‐Top Delivery Nanosystem for Powerful Dual‐Responsive Synergistic Colitis Treatment

Advanced Science, EarlyView.
A snap‐top delivery nanosystem based on an azobenzene metal–organic framework achieves targeted release of 6‐mercaptopurine via acid‐stable frameworks and hypoxia/pH dual‐responsive β‐cyclodextrin gates. This multifunctional platform integrates three synergistic mechanisms: precision drug delivery to inflammatory sites, intrinsic antioxidant properties
Xin Li, Miao Xu, Heran Li, Huan Jiang, Xin Wang, Lianjun Ma, Ying‐Wei Yang   +6 more
wiley   +1 more source

Recent Trends in Metabolomics by NMR Spectroscopy

Angewandte Chemie, EarlyView.
AI tools were applied to analyze more than 5 000 publications indexed in Scopus (2018–2025), identifying key trends and research directions in NMR‐based metabolomics. The artificial intelligence‐assisted workflow classified papers into six main fields of application, human health, food and nutrition, veterinary science, plants, environment, and ...
Giorgio Di Paco, Gaia Meoni, Veronica Ghini, Alessia Vignoli, Leonardo Tenori, Paola Turano, Claudio Luchinat   +6 more
wiley   +2 more sources

Flaxseed dietary fibers lower cholesterol and increase fecal fat excretion, but magnitude of effect depend on food type

Nutrition & Metabolism, 2012
Background Dietary fibers have been proposed to play a role in cardiovascular risk as well as body weight management. Flaxseeds are a good source of dietary fibers, and a large proportion of these are water-soluble viscous fibers. Method Here, we examine
Kristensen Mette, Jensen Morten G, Aarestrup Julie, Petersen Kristina EN, Søndergaard Lise, Mikkelsen Mette S, Astrup Arne   +6 more
doaj   +1 more source