Results 141 to 150 of about 373,383 (299)

Reduction of Intestinal Redox Potential by Coated Ferulic Acid Accelerates Microbial Restoration and Restricts Enterotoxigenic Escherichia coli Colonization in Weaned Piglets

Animal Research and One Health, EarlyView.
Schematic illustration showing the distinct microbe–host crosstalk patterns shaped by intestinal redox potential. The orange‐blue gradient indicated the redox potential transition from a low to a high potential microenvironment. Under low redox potential, Lactobacillus, Ligilactobacillus, Lachnospira, Roseburia, and Lachnoclostridium promoted ...
Ni Feng, Xin Guo, Changsong Fu, Weiyun Zhu, Yong Su   +4 more
wiley   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Micro‐ and nanoplastics in gastrointestinal disorders: Mapping the translational gap between exposure, biomonitoring, and pathogenic mechanisms

BMEMat, EarlyView.
This review highlights critical “translational gaps” in understanding micro‐ and nanoplastics impacts on gastrointestinal diseases, bridging exposure, detecting, and mechanistic toxicology. Abstract Micro‐ and nanoplastics (MNPs) have become pervasive environmental contaminants with increasing evidence linking them to adverse health outcomes.
Zhenli Diao, Yujie Luo, Chuanda Zhu, Yanwei Hu   +3 more
wiley   +1 more source

Fecal microbiome profile of dairy calves with different GI disease gradients

, 2021
Our objective was to associate the clinical symptoms of GI disease in neonatal dairy calves with changes in the fecal microbiome composition across different disease gradients and different ...
Washington State University (17855222)
core  

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

BMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen, Weichen Zhang, Gaoli Niu, Li Wang, Ruiyan Li, Yueyue Fan, Feixue Lu, Lingling Xu, Xiaoyuan Ji, Yong Kang   +9 more
wiley   +1 more source

Elucidating the separate and synergistic impacts of ruminal and hindgut acidosis on fermentation and microbiome of dairy cows

Journal of Dairy Science
: The aim of this study was to evaluate the short-term effects of both SARA and hindgut acidosis (HGA) on the ruminal and fecal fermentation and microbiome of dairy cows.
Patrick Biber, Rana Muhammad Atif, Thomas Hartinger, Nicole Reisinger, Tanya Gressley, Qendrim Zebeli, Ezequias Castillo-Lopez   +6 more
doaj   +1 more source

Probiotic spore‐based bioresponsive drug delivery for reversing inflammatory bowel disease and its associated anxiety and depression

BMEMat, EarlyView.
A probiotic spore‐based drug delivery system (BCS‐Que@ApNPs) provides excellent targeted delivery, bioresponsive drug release, and long‐term retention (over 48 h), making it suitable for oral treatment of inflammatory bowel disease and its associated anxiety and depression.
Qingling Song, Beiyang Xue, Yao Li, Chuangxi Zhou, Junfei Yang, Yunfei Li, Lingwen Ding, Yun Zhang, Hongjuan Zhao, Lei Wang   +9 more
wiley   +1 more source

Innovation of plant‐derived extracellular vesicles and interdisciplinary research: From discovery to biomedical applications

BMEMat, EarlyView.
Plant‐derived extracellular vesicles offer numerous advantages and are regarded as highly promising candidates in the field of biomedicine. Abstract Extracellular vesicles (EVs) are double‐membrane vesicular structures that can be secreted by nearly all living cells.
Zilin Li, Yi Wei, Ben Hu, Yafang Song, Xiaojia Chen, Nik Ahmad Nizam Nik Malek, Tongkai Chen   +6 more
wiley   +1 more source

Myoviridae as Part of Cattle Fecal Microbiome

, 2019
Double-stranded deoxyribonucleic acid (dsDNA) phages from the order of Caudovirales are the most abundant viruses in the microbiome of the mammalian digestive tract. There is increasing awareness of the role of phages in modulating bacterial composition in digestive compartments. Mammalian digestive microbiomes are generally dominated by members of the
openaire   +2 more sources

The altered TBI fecal microbiome is stable and functionally distinct

Frontiers in Molecular Neuroscience
Introduction Patients who suffer a traumatic brain injury (TBI) often experience chronic and sometimes debilitating sequelae. Recent reports have illustrated both acute and long-term dysbiosis of the gastrointestinal microbiome with significant alterations in composition and predicted functional consequences.
Richard B. Pyles, Aaron L. Miller, Randall J. Urban, Melinda Sheffield-Moore, Traver J. Wright, Carrie A. Maxwell, Kathleen M. Randolph, Christopher P. Danesi, Kristen A. McGovern, Jayson Vargas, Peyton Armstrong, Lisa Kreber, Giuliana Cumpa, Kevin Randall, Melissa Morrison, Brent E. Masel, Brent E. Masel   +16 more
openaire   +3 more sources