Results 51 to 60 of about 167,518 (291)

Dual‐Functional Ingestible Passive Capsules for High‐Throughput Intestinal Sampling with Sealed Containment and Targeted Drug Delivery

Advanced Robotics Research, EarlyView.
To address challenges in high‐throughput intestinal sampling with sealed containment and target drug delivery, we developed a dual‐functional ingestible passive capsule with a dual‐triggered control system based on pH‐response and mechanical actuation.
Libing Huang, Houyu Ling, Xizong Chen, Yufei Duan, Yu Liu, Shuntian Cai, Yandan Ren, Wenlong Li, Lei Ren, Miao Wang   +9 more
wiley   +1 more source

Prebiotic effects: metabolic and health benefits [PDF]

, 2010
The different compartments of the gastrointestinal tract are inhabited by populations of micro-organisms. By far the most important predominant populations are in the colon where a true symbiosis with the host exists that is a key for well-being and ...
Agnes Meheust, Anne L. McCartney, Audrey M. Neyrinck, Balsari, Ben, Bernd Stahl, Bernhard Watzl, Blaut, Brommage, Caderni, Caers, Cashman, Cashman, Chassard, Coudray, Cummings, Danielle Wolvers, de Vrese, Dughera, Engelhardt, Fava, Francisco Guarner, Franck, Frederique Respondek, Gibson, Girrbach, Glenn R. Gibson, Gray, Griffin, Hanai, Hania Szajewska, Harmsen, Hawthorne, Hudson, Hughes, Hussey, Ian Rowland, Irvine, Irvine, Kanauchi, Kelly, Kevin Whelan, Kim, Klobukowski, Kobayashi, Laurent Léotoing, Lesley Hoyles, Levitt, Lien do, Macfarlane, Macfarlane, Marcel Roberfroid, Marie-Jeanne Davicco, Mathey, Morand, Murphy, Nathalie M. Delzenne, Ng, O'Connor, O'May, Ohta, Ohta, Patrice D. Cani, Perrin, Pierre, Quigley, Rayssiguier, Reddy, Remesy, Reshef, Reuter, Richardson, Roberfroid, Roberfroid, Roberfroid, Roberfroid, Roberfroid, Robert Rastall, Rondon, Rowland, Sakaguchi, Schaafsma, Sellon, Siong, Suau, Taper, van Dokkum, Veronique Coxam, Vulevic, Wada, Walker, Wilson, Yohann Wittrant, Zoetendal, Zoetendal   +94 more
core   +3 more sources

High Humidity Exacerbates Psoriasiform Skin Disease Relapse by Increasing Tissue‐Resident Memory T Cells via Altering Skin Microbiota

Advanced Science, EarlyView.
We demonstrated that high humidity worsened psoriasis relapse in murine psoriasiform skin inflammation by increasing skin‐resident memory CD8+ cells via upregulating IL‐15Rα on keratinocytes. The increases in IL‐15Rα and memory CD8+ cells were attributed to S. nepalensis and its metabolite ADMA in skin exposed to high humidity.
Chun‐Ling Liang, Yuchao Chen, Chuanjian Lu, Huazhen Liu, Fenglian Qin, Sisi Dai, Feifei Qiu, Haiming Chen, Weihui Lu, Jonathan S. Bromberg, Zhenhua Dai   +10 more
wiley   +1 more source

Validation of a batch cultivation protocol for fecal microbiota of Kenyan infants

BMC Microbiology, 2023
Background The combination of cultivation studies with molecular analysis approaches allows characterization of the complex human gut microbiota in depth. In vitro cultivation studies of infants living in rural sub-Saharan Africa are scarce.
Carole Rachmühl, Christophe Lacroix, Ambra Giorgetti, Nicole U. Stoffel, Michael B. Zimmermann, Gary M. Brittenham, Annelies Geirnaert   +6 more
doaj   +1 more source

Gut microbiota changes associated with Clostridioides difficile infection and its various treatment strategies

Gut Microbes, 2023
Human gut microbiota are critical to both the development of and recovery from Clostridioides difficile infection (CDI). Antibiotics are the mainstay of CDI treatment, yet inherently cause further imbalances in the gut microbiota, termed dysbiosis ...
Anne J. Gonzales-Luna, Travis J. Carlson, Kevin W. Garey   +2 more
doaj   +1 more source

Effect of Lactobacillus rhamnosus HN001 and Bifidobacterium longum BB536 on the healthy gut microbiota composition at phyla and species level: a preliminary study [PDF]

, 2017
AIM: To evaluate the ability of Lactobacillus rhamnosus HN001 and Bifidobacterium longum BB536 to colonize the intestinal environment of healthy subjects and modify the gut microbiota composition.
De Grandi, Roberta, De Vecchi, Elena, Drago, Lorenzo, Stronati, Laura, Toscano, Marco   +4 more
core   +1 more source

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

Advanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol, Lihi Gur‐Arie, Netanel Tzarum, Tamara Wellins, Naama Katsowich, Miriam Ravins, Michal Bejerano‐Sagie, Klil Cohen, Oded Livnah, Joshua N. Adkins, Ernesto Nakayasu, Alexei Savchenko, Yeu Khai Choong, Nikhil Kumar Tulsian, Saturo Machida, Sigal Ben‐Yehuda, Yael Litvak, J. Sivaraman, Ilan Rosenshine   +18 more
wiley   +1 more source

Spatial host-microbiome profiling demonstrates bacterial-associated host transcriptional alterations in pediatric ileal Crohn’s disease

Microbiome
Background Crohn’s disease (CD) is a chronic inflammatory bowel disease involving complex relationships between the gut microbiome and host immune system.
Sooyoung Jang, Eun Joo Lee, Sowon Park, Hyeji Lim, Byungsoo Ahn, Yoon Huh, Hong Koh, Yu Rang Park   +7 more
doaj   +1 more source

The fecal resistome of dairy cattle is associated with diet during nursing. [PDF]

, 2019
Antimicrobial resistance is a global public health concern, and livestock play a significant role in selecting for resistance and maintaining such reservoirs.
DePeters, Edward J, Johnson, Daisy, Lemay, Danielle G, Liu, Jinxin, Maldonado-Gomez, Maria X, Mills, David A, Taft, Diana H, Treiber, Michelle L   +7 more
core   +1 more source

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source