Results 61 to 70 of about 408,278 (302)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Fecal microbiota transplantation. [PDF]

, 2022
Study aim: to describe fecal microbiota transplantation methods, indications, fecal preparation and complications of this procedure. Study methodology: in Pubmed data base was entered key words fecal microbiota transplantation and analyzed studies in ...
Stonytė, Ramutė,
core  

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Application of Dominant Gut Microbiota Promises to Replace Fecal Microbiota Transplantation as a New Treatment for Alzheimer’s Disease

, 2023
Several studies have confirmed that the pathophysiological progression of Alzheimer’s disease (AD) is closely related to changes in the intestinal microbiota; thus, modifying the intestinal microbiota has emerged as a new way to treat AD. Effective
Huan Yang, Yinhui Liu, Li Tang, Mufan Li, Shu Wen, Chenyi Shao   +5 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Molecular characterisation of selected gastrointestinal microbiota in South African HIV-positive patients during HAART [PDF]

, 2012
Includes bibliographical references.Progression of the HIV disease is characterised by a massive depletion of CD4+ T cells and it has been shown that patients living with a more advanced HIV infection have a higher risk of developing diarrhoea due to the
Du Plessis, Sarah Jane
core   +1 more source

Spatial host-microbiome profiling demonstrates bacterial-associated host transcriptional alterations in pediatric ileal Crohn’s disease

Microbiome
Background Crohn’s disease (CD) is a chronic inflammatory bowel disease involving complex relationships between the gut microbiome and host immune system.
Sooyoung Jang, Eun Joo Lee, Sowon Park, Hyeji Lim, Byungsoo Ahn, Yoon Huh, Hong Koh, Yu Rang Park   +7 more
doaj   +1 more source

The fecal microbiota of healthy donor horses and geriatric recipients undergoing fecal microbial transplantation for the treatment of diarrhea.

PLoS ONE, 2020
Background and aimsFecal microbial transplantation (FMT), a treatment for certain gastrointestinal conditions associated with dysbiosis in people, is also empirically employed in horses with colitis.
Caroline A McKinney, Bruno C M Oliveira, Daniela Bedenice, Mary-Rose Paradis, Melissa Mazan, Sophie Sage, Alfredo Sanchez, Giovanni Widmer   +7 more
doaj   +1 more source

Validation of a batch cultivation protocol for fecal microbiota of Kenyan infants

BMC Microbiology, 2023
Background The combination of cultivation studies with molecular analysis approaches allows characterization of the complex human gut microbiota in depth. In vitro cultivation studies of infants living in rural sub-Saharan Africa are scarce.
Carole Rachmühl, Christophe Lacroix, Ambra Giorgetti, Nicole U. Stoffel, Michael B. Zimmermann, Gary M. Brittenham, Annelies Geirnaert   +6 more
doaj   +1 more source

Alteration of Gut Microbiota in Carbapenem-Resistant Enterobacteriaceae Carriers during Fecal Microbiota Transplantation According to Decolonization Periods

, 2021
Fecal microbiota transplantation (FMT) has been suggested as an alternative therapeutic option to decolonize carbapenem-resistant Enterobacteriaceae (CRE).
Ki Tae Suk, Jin-Jae Lee, Heung-Jeong Woo, Bong-Soo Kim, Dongeun Yong, Dong Joon Kim, Seung Soon Lee   +6 more
core   +1 more source