Results 111 to 120 of about 80,269 (322)

Neuroprotective Effects of Time‐Restricted Feeding Combined With Different Protein Sources in MPTP‐Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism

Advanced Science, EarlyView.
Time‐restricted feeding (TRF) exerts protein‐dependent neuroprotective effects in an MPTP‐induced Parkinson's disease model. In casein‐fed mice, TRF improves gut barrier integrity and reduces neuroinflammation, possibly via modulation of Allobaculum and BCAAs.
Ting Li, Jian Wu, Sheng‐Yang Zhou, Ming‐An Li, Li‐Ping Zhao, Ao Wang, Yi‐Zhi Song, Wen‐Yan Huang, Lu‐Lu Tan, Chen‐Meng Qiao, Wei‐Jiang Zhao, Chun Cui, Yan‐Qin Shen   +12 more
wiley   +1 more source

Intestinal fungi contribute to development of alcoholic liver disease [PDF]

, 2017
This study was supported in part by NIH grants R01 AA020703, U01 AA021856 and by Award Number I01BX002213 from the Biomedical Laboratory Research & Development Service of the VA Office of Research and Development (to B.S.). K.H.
Ali Keshavarzian, An-Ming Yang, Bernd Schnabl, Bode, Chien-Sheng Chen, Claus Hellerbrand, Cristina Llorente, Derrick E. Fouts, Ece A. Mutlu, Fettweis, Fouts, Gordon D. Brown, Guadalupe Garcia-Tsao, Hal M. Hoffman, Jun Xu, Karen Beeri, Katrin Hochrath, Kelvin Moncera, Kim Freese, Lee, Lirui Wang, Liu, Manolito G. Torralba, Peng Chen, Peter Stärkel, Phillipp Hartmann, Ramon Bataller, Samuel B. Ho, Sena Bluemel, Serene M.L. Lee, Sokol, Tatiana Kisseleva, Tatsuo Inamine, Wagner, Wajahat Z. Mehal, Yamahiro, Yang, Yukinori Koyama   +37 more
core   +3 more sources

Gut Bacterium Lysinibacillus Sphaericus Exacerbates Aspirin‐induced Intestinal Injury by Production of Carboxylesterase EstB

Advanced Science, EarlyView.
Schematic overview illustrating the detrimental role of gut microbiota in aspirin‐induced intestinal injury. L. sphaericus and its secreted carboxylesterase EstB are identified as key drivers that catalyze aspirin hydrolysis into salicylic acid, thereby exacerbating intestinal injury. Inhibition of EstB by the dietary compound flavanomarein effectively
Zeyu Zhao, Qing Li, Xiaowu Bai, Ertao Zhai, Weigang Dai, Yan Qian, Tianhao Zhang, Zhixin Huang, Ziyu Huang, Fangang Meng, Jianhui Chen, Tao Zuo, Shirong Cai, Risheng Zhao   +13 more
wiley   +1 more source

Extreme Dysbiosis of the Microbiome in Critical Illness. [PDF]

, 2016
Critical illness is hypothesized to associate with loss of "health-promoting" commensal microbes and overgrowth of pathogenic bacteria (dysbiosis). This dysbiosis is believed to increase susceptibility to nosocomial infections, sepsis, and organ failure.
Christine Baird, Christine Vis-Kampen, Daniel McDonald, Daren Heyland, Gail Ackermann, Judy King, Karrie Derenski, Ludmila Khailova, Margot Lemieux, Paul E. Wischmeyer, Rob Knight, Rosemary Kozar, Susannah Green Tringe   +12 more
core   +2 more sources

Phocaeicola coprophilus‐Derived 6‐Methyluracil Attenuates Radiation‐Induced Intestinal Fibrosis by Suppressing the IDO1‐Kynurenine‐AHR Axis

Advanced Science, EarlyView.
IR‐induced dysbiosis depletes P. coprophilus and its metabolite 6‐methyluracil, leading to disinhibition of the IDO1‐Kyn‐AHR axis. This results in sustained fibroblast activation and collagen deposition, driving radiation induced intestinal fibrosis. ABSTRACT Therapeutic options for radiation‐induced intestinal fibrosis (RIF) remain limited. This study
Jiaxin Zhang, Zhen Wang, Shuang Li, Chao Luo, Han Li, Shengjie Ma, Pai Wang, Heshi Liu, Lijun Sun, Yue Yin, Weizhen Zhang, Quan Wang   +11 more
wiley   +1 more source

Transplanting fecal material from wild‐type mice fed black raspberries alters the immune system of recipient mice

Food Frontiers, 2020
By constantly stimulating intestinal immunity, gut microbes play important regulatory roles, and their possible involvement in human physical and mental disorders beyond intestinal diseases suggests the importance of maintaining homeostasis in the gut ...
Yi‐Wen Huang, Pan Pan, Carla Elena Echeveste, Hsin‐Tzu Wang, Kiyoko Oshima, Chien‐Wei Lin, Martha Yearsley, Jianbo Xiao, Jiebiao Chen, Chongde Sun, Jianhua Yu, Li‐Shu Wang   +11 more
doaj   +1 more source

European consensus conference on faecal microbiota transplantation in clinical practice [PDF]

, 2017
Faecal microbiota transplantation (FMT) is an important therapeutic option for Clostridium difficile infection. Promising findings suggest that FMT may play a role also in the management of other disorders associated with the alteration of gut microbiota.
Aloi, Marina, Arkkila, Perttu, Cammarota, Giovanni, De Groot, Pieter, de Vos, Willem M., European FMT Working Grp, Gasbarrini, Antonio, Gasbarrini, Giovanni, Hart, Ailsa, Hoegenauer, Christoph, Ianiro, Gianluca, Kump, Patrizia, Link, Alexander, Lopez-Sanroman, Antonio, Malfertheiner, Peter, Masucci, Luca, Mattila, Eero, Milosavljevic, Tomica, Molinaro, Antonio, Nieuwdorp, Max, Pintus, Cristina, Rajilic-Stojanovic, Mirjana, Sanguinetti, Maurizio, Satokari, Reetta, Scaldaferri, Franco, Segal, Jonathan, Simren, Magnus, Sokol, Harry, Tilg, Herbert   +28 more
core   +2 more sources

Gut Microbiota‐Non‐Coding RNA Axis in Immune Modulation and Disease: From Mechanisms to Clinical Translation

Advanced Science, EarlyView.
ABSTRACT Immune homeostasis is indispensable for preserving organismal integrity, orchestrated through complex molecular networks encompassing immune cell dynamics, microbial cues, and epigenetic regulation. Among these, the gut microbiota‐non‐coding RNA (ncRNA) axis has recently garnered substantial attention as a multifaceted modulator of host ...
Bonan Chen, Guoming Chen, Xieyuan Leng, Qianfan Li, Wenhao Wu, Wenqiu Wu, Zixuan Liu, Zilan Zhong, Xiaohong Zheng, Wei Kang, Fazheng Ren, Yigan Zhang, Juan Chen   +12 more
wiley   +1 more source

Transplanting Fecal Virus-Like Particles Reduces High-Fat Diet-Induced Small Intestinal Bacterial Overgrowth in Mice

Frontiers in Cellular and Infection Microbiology, 2019
Fecal microbiota transplantation (FMT) is an effective tool for treating Clostridium difficile infection in the setting of dysbiosis of the intestinal microbiome. FMT for other forms of human disorders linked to dysbiosis have been less effective.
Derek M. Lin, Britt Koskella, Nathaniel L. Ritz, Dongdong Lin, Amanda Carroll-Portillo, Henry C. Lin, Henry C. Lin   +6 more
doaj   +1 more source

Efficacy and safety of fecal microbiota transplantation in the treatment of ulcerative colitis: a systematic review and meta-analysis [PDF]

, 2023
Jing Feng, Yexin Chen, Yan Liu, Lin Lin, Xiujuan Lin, Wenxiu Gong, Rongmu Xia, Jianquan He, Jianwen Sheng, Huimei Cai, Chuanxing Xiao   +10 more
openalex   +1 more source