Integrative Zoology, EarlyView.18 days of predator odor exposure altered gut microbiota, increased anxiety‐like behaviors, and elevated hypothalamic–pituitary–adrenal axis activity in Brandt's voles, with males showing behavioral habituation and females remaining sensitive. Cecal microbiota transplantation experiments confirmed that only female recipients of microbiota from predator‐
Chen Gu +6 more
wiley +1 more source
Blubber Thickening Driven by UCP1 Inactivation: Insights from a Cetacean‐Like Transgenic Mouse Model
Integrative Zoology, EarlyView.UCP1 inactivation of cetaceans in mice drives BAT whitening and iWAT hyperplasia, promoting fat accumulation for aquatic adaptation. Abstract Cetaceans possess thick blubber, a specialized adipose tissue essential for thermal insulation, a streamlined body form, energy storage, and buoyancy. However, the mechanisms that underpin this adaptation are not
Qian Zhang +5 more
wiley +1 more source
Fecal virome transplantation is sufficient to alter fecal microbiota and drive lean and obese body phenotypes in mice [PDF]
, 2023 Joshua M. Borin +11 more
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Aberrant Growth in 5‐Year‐Old Children After Antibiotics in the First Week of Life
Acta Paediatrica, EarlyView.ABSTRACT Aim We examined the relationship between early‐life antibiotics, different regimens, and growth until age five years. Methods Data from two parallel birth cohorts were analysed: 128 healthy term‐born children and 147 term‐born children who received antibiotics for suspected neonatal sepsis, randomised across three regimens: Amoxicillin ...
Lisanne M. van Leeuwen +6 more
wiley +1 more source
Alimentary Pharmacology &Therapeutics, EarlyView.In‐depth multiomics analyses revealed that the gut microbiota in patients with CPH is dysbiotic. Altered gut microbiota plays an important role in the progression of CPH and affects the host's arginine metabolism to promote arginine biosynthesis. The pro‐inflammatory effects of certain gut bacteria induce iNOS expression, which together act on the ...
Qun Zhang +15 more
wiley +1 more source
Transplantation of intestinal microbiota: therapeutic potential at diseases of digestive organs
Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2014 The aim of review. To analyze accumulated world data on human fecal microbiota transplantation (FMT) at treatment of digestive diseases.Summary. Review highlights basic problems of fecal microbiota transplantation — i.e.
E. V. Shrayner +3 more
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Alimentary Pharmacology &Therapeutics, EarlyView.In a large‐scale, multiple‐site Danish faecal microbiota transplantation (FMT) system, the cure rates in patients with Clostridioides difficile infection treated with encapsulated FMT were improved following exclusion of three low‐performing donors and implementation of a two‐dose FMT regimen.
Sara Ellegaard Paaske +17 more
wiley +1 more source
Current status, complications and prospects of fecal microbiota transplantation therapy [PDF]
, 2021 Tadashi Ohara
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Novel approaches for drug development against chronic primary pain: A systematic review
British Journal of Pharmacology, EarlyView.Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Fecal Microbiota Transplantation for Treatment of Recurrent Clostridium difficile Infections Using Recipient-Directed Donors Sero-Matched for Latent Viruses: The University of Pittsburgh Medical Center (UPMC) Experience [PDF]
, 2016 Scott Curry +4 more
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