Results 191 to 200 of about 29,988 (285)

Changes in Colonic Bile Acid Composition following Fecal Microbiota Transplantation Are Sufficient to Control Clostridium difficile Germination and Growth

, 2016
Alexa R. Weingarden, Peter I. Dosa, Erin DeWinter, Clifford J. Steer, Megan Shaughnessy, James R. Johnson, Alexander Khoruts, Michael J. Sadowsky   +7 more
openalex   +2 more sources

Microbiome‐Informed Dosing: Exploring Gut Microbial Communities Impact on Mycophenolate Enterohepatic Circulation and Therapeutic Target Achievement

Clinical Pharmacology &Therapeutics, Volume 118, Issue 6, Page 1477-1488, December 2025.
Pharmacomicrobiomics is an emerging field due to important microbiome effects on pharmacokinetics and clinical outcomes. However, the application of this knowledge remains limited. Mycophenolic acid (MPA) is the primary active metabolite of the immunosuppressant, mycophenolate mofetil (MMF).
Abdelrahman Saqr, Shen Cheng, Mahmoud Al‐Kofahi, Christopher Staley, Pamala A. Jacobson   +4 more
wiley   +1 more source

Knowledge and Acceptability of Fecal Microbiota Transplantation Among Patients, Caregivers, and Health Care Providers in Ethiopia. [PDF]

Open Forum Infect Dis
Shackelford BB, Kedir K, Babiker A, Sintayehu B, Negash AA, Abdissa A, Taye WA, Beyene E, Woodworth MH, Hennink MM.   +9 more
europepmc   +1 more source

Pharmacomicrobiomics

Clinical Pharmacology &Therapeutics, Volume 118, Issue 6, Page 1366-1377, December 2025.
Oral medications encounter gut commensal microbes that participate directly and indirectly in drug effects through metabolism, interactions with drug metabolites, or production of substrates that compete with drugs for drug‐metabolizing enzymes, consequently influencing drug pharmacokinetics.
Naomi Gronich, Naama Geva‐Zatorsky, Rachel Herren, Libusha Kelly, Ziv Cohen, Haiying Zhou, Yi‐Ching Chen, Khalid Shah, Talin A. Robinson‐Catala, Grecia Frisby, Jason H. Karnes, Lisl Shoda   +11 more
wiley   +1 more source

Fecal microbiota transplantation in pigs: current status and future perspective. [PDF]

Anim Microbiome
Rahman R, Marcolla CS, Willing BP.
europepmc   +1 more source

Diarrhea after fecal microbiota transplantation for recurrent Clostridioides difficile infection [PDF]

, 2019
Cole Krensky, Susan M. Poutanen, Susy Hota   +2 more
openalex   +1 more source

A Fast Path from Innovation to Safe and Effective Medicines

Clinical Pharmacology &Therapeutics, Volume 118, Issue 6, Page 1392-1404, December 2025.
Consistent progress in medicines development has allowed both for de novo treatment options and for the refinement of existing products that improve effectiveness or reduce harm. Nonetheless, unmet medical needs persist, particularly in rare diseases, pediatrics and underserved populations.
Peter Arlett, Falk Ehmann, Ralf Herold, Evdokia Korakianiti, Pierpaolo Moscariello, Liese Barbier, Iordanis Gravanis, Frank Pétavy, Emmanuel Cormier, Andrew Thomson, Spiros Vamvakas, Steffen Thirstrup   +11 more
wiley   +1 more source

Butyrate‐Mediated Upregulation of Insulin Pathway Gene Expression Suggests Potential Antidiabetic Effects

Drug Development Research, Volume 86, Issue 8, December 2025.
ABSTRACT Type 2 diabetes (T2D) is a major cause of morbidity in developed countries and involves insulin resistance, a failure to correctly respond to insulin. Numerous studies in rodent T2D models suggested that the short‐chain fatty acid butyrate, produced by gut microbiota species through fermentation of dietary fibers, improves T2D symptoms.
Elad Shapira, Irena Voinsky, Hana Klin, David Gurwitz   +3 more
wiley   +1 more source

Is Fecal Microbiota Transplantation Applicable for the Treatment of Irritable Bowel Syndrome? Time for Precision Medicine. [PDF]

J Neurogastroenterol Motil
Gweon TG.
europepmc   +1 more source

Exploring Fecal Microbiota Transplantation for Modulating Inflammation in Parkinson’s Disease: A Review of Inflammatory Markers and Potential Effects [PDF]

Karol Sadowski, Weronika Zając, Łukasz Milanowski, Dariusz Koziorowski, Monika Figura   +4 more
openalex   +1 more source