Understanding extracellular vesicles in antiaging
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad +3 more
wiley +1 more source
Global research trends in fecal microbiota transplantation combined with immune checkpoint inhibitors for cancer immunotherapy: a bibliometric analysis. [PDF]
Hu Y, Hendi M, Du L, Chen X.
europepmc +1 more source
Periodontitis and metabolic dysfunction‐associated steatotic liver disease
Abstract Objective Periodontitis is a chronic inflammatory disease with systemic effects that extend beyond the oral cavity and contribute to systemic immune and metabolic dysregulation. Chronic liver diseases, particularly metabolic dysfunction‐associated steatotic liver disease (MASLD) and its progressive phenotypes, have emerged as major global ...
Rafael Scaf de Molon +6 more
wiley +1 more source
Water-responsive injectable hydrogel achieving rapid in situ gelation and long-term colonic mucoadhesion for efficient fecal microbiota transplantation. [PDF]
Chen Z +11 more
europepmc +1 more source
In this prospective cohort study, we profiled the blood microbiome in kidney transplant recipients over time. We detected a low abundance of microbial DNA in half of the blood specimens. In a small subset, we also detected gut bacterial taxa in the blood of kidney transplant recipients.
Alex DeVito +10 more
wiley +1 more source
Case Report: Fecal microbiota transplantation resensitizes advanced non-small cell lung cancer to platinum-based chemotherapy. [PDF]
Lee YJ +7 more
europepmc +1 more source
Dietary interventions in acute kidney injury: From molecular mechanism to clinical trials
Abstract Ageing impairs renal resilience with an elevated risk of frequent and harmful acute kidney injury (AKI) that causes substantial morbidity and mortality among hospitalized patients. Since different damaging stimuli at the molecular, cellular and functional level contribute to this loss in kidney function, AKI's pathophysiology is heterogeneous ...
Felix C. Koehler +2 more
wiley +1 more source
Safety and efficacy of fecal microbiota transplantation in solid cancers resistant to immune checkpoint inhibitors: results of the MITRIC trial. [PDF]
Ullern A +8 more
europepmc +1 more source
Translating gut microbiome research into therapies for type 1 diabetes
Abstract Type 1 diabetes (T1D) is characterised by the loss of functional pancreatic β‐cells, for which lifelong insulin therapy remains the standard of care. Given that the gut microbiome can influence host health and that shifts in gut microbial profiles have been observed in T1D, growing interest has emerged in the role of the gut microbiome in T1D,
Shanti P. Kok +2 more
wiley +1 more source
Validation of an Automated Fluorescence- and Image-Based Viable Cell Counting Method for Fecal Microbiota Transplantation Drug Products. [PDF]
Lang T +4 more
europepmc +1 more source

