Results 161 to 170 of about 738,105 (258)

Immunometabolic Modulation by Low‐Dose Sodium Butyrate: PI3K/Akt/mTOR Signalling Orchestrates Macrophage Polarization to Protect Against Clostridioides difficile Colitis

Immunology, EarlyView.
Clostridioides difficile toxins TcdA and TcdB enter intestinal epithelial cells (IECs) via specific receptors, disrupt tight‐junction integrity and activate PI3K/Akt/mTOR signalling, promoting inflammasome assembly and IL‐1β release. Toxin‐induced IEC apoptosis further weakens the epithelial barrier.
Sisi Zhang, Zhou Jingxiang, Caixia Tan, Yuanyuan Xiao, Ju Zou, Biyue Tian, Anhua Wu, Chunhui Li   +7 more
wiley   +1 more source

Fecal microbiota transplantation for marked colonic dilatation. [PDF]

Korean J Intern Med
Cho E, Lee JH, Hong JT, Kwon KS, Shin YW.   +4 more
europepmc   +1 more source

Evaluation of Clinical Practice Guidelines on Fecal Microbiota Transplantation in Adults: A Cross‐Sectional Study

Journal of Evidence-Based Medicine, EarlyView.
ABSTRACT Objective Fecal microbiota transplantation (FMT) is an emerging multi‐disease therapy, yet the quality and consistency of its available clinical practice guidelines (CPGs) remain unknown. This study aimed to systematically evaluate the quality, content coverage and recommendation consistency of FMT‐related guidelines and develop an ...
Mingjuan Zhao, Shaojie Li, Guang Fu, Tong Deng, Yinghui Jin, Yingjiang Ye, Zhiqiang Li   +6 more
wiley   +1 more source

A Refined Method for Fecal Microbiota Transplantation Using Nutella. [PDF]

Clin Transl Sci
Henriksen IW, Hansen CHF, Koch J, Sørensen DB, Nielsen DS, Bartholdy C, Hansen AK.   +6 more
europepmc   +1 more source

Postelectroacupuncture Fecal Microbiota Transplantation (post‐EA FMT) Regulates Gastrointestinal Hormones in Functional Dyspepsia Rats Is Associated With Modulation of the Intestinal Microbiota‐Bile Acid Metabolic Pathway

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background Electroacupuncture (EA) reshapes intestinal flora; whether post‐EA fecal microbiota transplantation (post‐EA FMT) regulates gastrointestinal hormones via the gut microbiota–bile acid (BA) pathway remains unclear. Methods Sham EA (SEA) served as control. Gastrointestinal hormones/motility were assessed post‐EA.
Yong‐Li Han, Dong‐Fang Shang, Juli Tang, Dong‐Dong Yu, Liang‐Yu Zhang, Jing Zhou, Qing‐Bo Wang   +6 more
wiley   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

Fecal Microbiota Transplantation as a Rescue Therapy for Refractory <i>Clostridioides difficile</i> Infection in a Patient With Lupus. [PDF]

Case Rep Infect Dis
Pinzón MA, Betancur JF, Bolaño APS, Boada-Garnica JA, Llano JF, Ramírez B.   +5 more
europepmc   +1 more source

The Oral‐Gut Axis: Bidirectional Interactions Between Microbiome and Diseases

Journal of Periodontal Research, EarlyView.
This study aims to summarize the mechanisms underlying ectopic colonization of the gut by oral pathobionts and the microbial and host factors that regulate this process. ABSTRACT Increased colonization of typically oral microorganisms is frequently observed in the gut mucosa or lumen of individuals with gastrointestinal disorders, including patients ...
Shinya Ebihara, Nobuhiko Kamada
wiley   +1 more source

Fecal microbiota transplantation for the treatment of neurogenic rosacea: protocol of a randomized, blinded, placebo-controlled explorer study. [PDF]

Ann Med
Zhu X, Cheng L, Li S, Guo D, Guo W, Du X, Yan R, Wang X, Yuan S, Chen M, Zhang W, Li S, Li F, Zhang L.   +13 more
europepmc   +1 more source

The Oral‐Hepatic Axis: Epidemiological and Mechanistic Links Between Periodontal and Liver Diseases

Journal of Periodontal Research, EarlyView.
This review summarizes current epidemiological, clinical and mechanistic evidence linking periodontitis and chronic liver diseases, highlighting the oral‐gut‐liver axis, shared immunometabolic and nutritional pathways and opportunities for integrated preventive and therapeutic strategies.
Sinem Esra Sahingur, Kinga Grzech‐Leśniak, Samuel F. Suslavich, Janina Golob Deeb   +3 more
wiley   +1 more source