Results 71 to 80 of about 80,269 (322)

Fecal Microbiota Transplantation as New Therapeutic Avenue for Human Diseases

Journal of Clinical Medicine, 2022
The human body is home to a variety of micro-organisms. Most of these microbial communities reside in the gut and are referred to as gut microbiota. Over the last decades, compelling evidence showed that a number of human pathologies are associated with ...
Manuele Biazzo, Gabriele Deidda
semanticscholar   +1 more source

Pre‐Administration of Akkermansia Muciniphila Prevents the Development of Severe Acute Graft‐Versus‐Host Disease in Systemic Organs

Advanced Science, EarlyView.
Akkermansia muciniphila, a next‐generation probiotic, alleviates acute graft‐versus‐host disease (aGvHD) following allogeneic hematopoietic stem cell transplantation (HSCT) by providing protective effects across multiple organs. Pre‐colonization with A.
Jeong‐Eun Han, Dae‐Seong Lee, Su‐Won Jeong, Ji‐Hyun Yun, Seomin Kang, Seoyoung Jang, EunAh Lee, Ju Hye Baek, Che Ok Jeon, Jin‐Woo Bae   +9 more
wiley   +1 more source

A shared mucosal gut microbiota signature in primary sclerosing cholangitis before and after liver transplantation

Hepatology, EarlyView., 2022
In this study of the gut mucosal microbiota in primary sclerosing cholangitis (PSC), we found consistent microbiota features associated with PSC and recurrent PSC, PSC with inflammatory bowel disease and a persistent gut dysbiosis after liver transplantation Abstract Background and Aims Several characteristic features of the fecal microbiota have been ...
Mikal Jacob Hole, Kristin Kaasen Jørgensen, Kristian Holm, Peder R. Braadland, Malin Holm Meyer‐Myklestad, Asle Wilhelm Medhus, Dag Henrik Reikvam, Alexandra Götz, Krzysztof Grzyb, Kirsten Muri Boberg, Tom Hemming Karlsen, Martin Kummen, Johannes R. Hov   +12 more
wiley   +1 more source

Refining microbiome diversity analysis by concatenating and integrating dual 16S rRNA amplicon reads

npj Biofilms and Microbiomes
Understanding the role of human gut microbiota in health and disease requires insights into its taxonomic composition and functional capabilities.
Kyoung Su Kim, Jihye Noh, Bong-Soo Kim, Hong Koh, Dong-Woo Lee   +4 more
doaj   +1 more source

Gut microbiota decreased inflammation induced by chronic unpredictable mild stress through affecting NLRP3 inflammasome

Frontiers in Cellular and Infection Microbiology, 2023
Dysbiosis of the gut microbiota is associated with the development of depression, but the underlying mechanism remains unclear. The aim of this study was to determine the relationship between microbiota and NLRP3 inflammasome induced by chronic ...
Li Huang, Li Huang, Zewei Ma, Zewei Ma, Xiaolei Ze, Xinrui Zhao, Xinrui Zhao, Meilin Zhang, Meilin Zhang, Xia Lv, Xia Lv, Yunqin Zheng, Yunqin Zheng, Huan Liu, Huan Liu   +14 more
doaj   +1 more source

Perceptions of fecal microbiota transplantation for Clostridium difficile infection: factors that predict acceptance. [PDF]

, 2016
BackgroundDespite the effectiveness of fecal microbiota transplantation (FMT) for treating recurrent Clostridium difficile (C. difficile) infection, some patients are reluctant to accept this therapy.
Chen, Lea Ann, Hirsh, Jacqueline, Malter, Lisa, Mone, Anjali, Park, Leslie, Poles, Michael A, Price, Jennifer C, Tzimas, Demetrios   +7 more
core   +1 more source

Development of an Ex Vivo Organ Culture Technique to Evaluate Probiotic Utilization in IBD [PDF]

, 2016
The consistent technical and conceptual progress in the study of the microbiota has led novel impulse to the research for therapeutical application of probiotic bacteria in human pathologies, such as inflammatory bowel disease (IBD).
DELLE FAVE, Gianfranco, Lanini, Claudio, Martorelli, M, Pagnini, C   +3 more
core   +1 more source

The Importance of Microbiota and Fecal Microbiota Transplantation in Pancreatic Disorders

Diagnostics
The role of the intestinal microbiota in the diagnosis and treatment of pancreatic diseases is increasingly significant. Consequently, fecal microbiota transplantation (FMT) is emerging as a promising therapeutic avenue for various pancreatic disorders ...
A. Boicean, Cristian Ichim, Samuel-Bogdan Todor, Paula Anderco, M. L. Popa   +4 more
semanticscholar   +1 more source

Fecal Microbiota Transplantation (FMT) as an Adjunctive Therapy for Depression—Case Report

Frontiers in Psychiatry, 2022
Depression is a debilitating disorder, and at least one third of patients do not respond to therapy. Associations between gut microbiota and depression have been observed in recent years, opening novel treatment avenues.
J. P. Doll, Jorge F Vázquez-Castellanos, Annalisa Schaub, N. Schweinfurth, Cedric Kettelhack, E. Schneider, G. Yamanbaeva, Laura Mählmann, S. Brand, C. Beglinger, S. Borgwardt, J. Raes, A. Schmidt, U. Lang   +13 more
semanticscholar   +1 more source

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

Advanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang, Zibin Li, Yao Xiao, Ji Bian, Caian He, Chao Liu, Lan Gong, Lin Han, Zhigang Liu, Min Wang   +9 more
wiley   +1 more source