Results 51 to 60 of about 738,105 (258)

Fecal Microbiota Transplantation Is Effective in Relieving Visceral Hypersensitivity in a Postinfectious Model [PDF]

, 2018
Aim. To investigate the effect of fecal microbiota transplantation on visceral hypersensitivity compared withBifidobacterium longum.Methods. Mice visceral hypersensitivity was induced byTrichinella spiralis.
Tao Bai, Xiaohua Hou, Lei Zhang, Wei Qian, Jun Song, Huan Wang   +5 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Pediatric <i>Clostridiodes difficile</i> infection with toxic megacolon successfully treated with fecal microbiota transplantation. [PDF]

JPGN Rep
Abstract The rising incidence of pediatric Clostridioides difficile infection (CDI), particularly in medically complex patients, calls for novel, individualized treatments. While fecal microbiota transplantation (FMT) is well‐described for recurrent CDI, this report describes the first pediatric case of fulminant CDI with toxic megacolon successfully ...
McCarney D, Chen P, Simes J, Kahn SA.
europepmc   +2 more sources

Fecal Microbiota Transplantation in Dogs

, 2021
In people, fecal microbiota transplantation is recognized as the best treatment modality for recurrent Clostridioides difficile infection in people, and its value is currently investigated in the treatment of other diseases associated with an abnormal ...
Chaitman, Jennifer, Gaschen, Frédéric, Jennifer Chaitman, Frédéric Gaschen   +3 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Refining microbiome diversity analysis by concatenating and integrating dual 16S rRNA amplicon reads

npj Biofilms and Microbiomes
Understanding the role of human gut microbiota in health and disease requires insights into its taxonomic composition and functional capabilities.
Kyoung Su Kim, Jihye Noh, Bong-Soo Kim, Hong Koh, Dong-Woo Lee   +4 more
doaj   +1 more source

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

Advanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He, Jielan Mi, Zhiping Zhao, Xiao Zhang, Zhihan Yang, Kun Yue, Yuanming Huang, Liqiong Song, Xiaoting Wen, Jianguo Xu, Zhihong Ren   +10 more
wiley   +1 more source

Using fecal microbiota transplantation for animal health (review)

Ветеринария сегодня
Fecal microbiota transplantation is a procedure when fecal matter from a healthy donor is administered into the intestinal tract of a recipient in order to restore microbial balance and strengthen immune responses.
H. Yu. Drobot, S. K. Shebeko, A. M. Ermakov   +2 more
doaj   +1 more source

Effect of Vegan Fecal Microbiota Transplantation on Carnitine‐ and Choline‐Derived Trimethylamine‐N‐Oxide Production and Vascular Inflammation in Patients With Metabolic Syndrome

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundIntestinal microbiota have been found to be linked to cardiovascular disease via conversion of the dietary compounds choline and carnitine to the atherogenic metabolite TMAO (trimethylamine‐N‐oxide).
Loek P. Smits, Ruud S. Kootte, Evgeni Levin, Andrei Prodan, Susana Fuentes, Erwin G. Zoetendal, Zeneng Wang, Bruce S. Levison, Maartje C. P. Cleophas, E. Marleen Kemper, Geesje M. Dallinga‐Thie, Albert K. Groen, Leo A. B. Joosten, Mihai G. Netea, Erik S. G. Stroes, Willem M. de Vos, Stanley L. Hazen, Max Nieuwdorp   +17 more
doaj   +1 more source

Metatranscriptome analysis of the human fecal microbiota reveals subject-specific expression profiles, with genes encoding proteins involved in carbohydrate metabolism being dominantly expressed [PDF]

, 2010
The human gastrointestinal (GI) tract provides home to a complex microbial community, collectively termed microbiota. Although major efforts have been made to describe the diversity and stability of the microbiota, functional studies have been largely ...
Vos, W.M., de, Kleerebezem, M., Smidt, H., Zoetendal, E.G., Hauke Smidt, Booijink, C.C.G.M., Erwin G. Zoetendal, Carien C. G. M. Booijink, Boekhorst, J., te, Michiel Kleerebezem, Jos Boekhorst, Willem M. de Vos   +11 more
core   +1 more source