Results 31 to 40 of about 2,134 (91)

Remdesivir Derivative VV116 Is a Potential Broad-Spectrum Inhibitor of Both Human and Animal Coronaviruses

Viruses, 2023
Coronaviruses represent a significant threat to both human and animal health, encompassing a range of pathogenic strains responsible for illnesses, from the common cold to more severe diseases.
Weiyong Liu, Min Zhang, Chengxiu Hu, Huijuan Song, Yi Mei, Yingle Liu, Qi Zhang   +6 more
doaj   +1 more source

Genetic Characteristics and Research Progress of Feline Coronavirus

Shiyan dongwu yu bijiao yixue
Feline coronavirus (FCoV) is classified into two biotypes: feline infectious peritonitis virus (FIPV) and feline enteric coronavirus (FECV). FIPV and FECV might evolve and mutate via genetic recombination and mutation, leading to novel subtypes and ...
TAO Lingyun
doaj   +1 more source

Reverse Genetics for Type I Feline Coronavirus Field Isolate To Study the Molecular Pathogenesis of Feline Infectious Peritonitis

mBio, 2018
Feline infectious peritonitis (FIP), one of the most important lethal infections of cats, is caused by feline infectious peritonitis virus (FIPV), the high-virulence biotype of feline coronaviruses (FCoVs).
Rosina Ehmann, Claudia Kristen-Burmann, Barbara Bank-Wolf, Matthias König, Christiane Herden, Torsten Hain, Heinz-Jürgen Thiel, John Ziebuhr, Gergely Tekes   +8 more
doaj   +1 more source

Morphology of Carbides Crystallizing in Fe-C-V and Fe-C-V-Si Alloys

Archives of Metallurgy and Materials, 2014
Fe-C-V alloys with high vanadium content are included in the family of white cast irons, because all carbon present in this material is bound into vanadium carbides.
Kawalec M.
doaj   +1 more source

Crystallization of Feline Coronavirus Mpro With GC376 Reveals Mechanism of Inhibition

Frontiers in Chemistry, 2022
Coronaviruses infect a variety of hosts in the animal kingdom, and while each virus is taxonomically different, they all infect their host via the same mechanism.
Jimmy Lu, Jimmy Lu, Sizhu Amelia Chen, Sizhu Amelia Chen, Muhammad Bashir Khan, Raelynn Brassard, Raelynn Brassard, Elena Arutyunova, Elena Arutyunova, Tess Lamer, Wayne Vuong, Conrad Fischer, Howard S. Young, John C. Vederas, M. Joanne Lemieux, M. Joanne Lemieux   +15 more
doaj   +1 more source

Effect of Microstructure of Fe-C-V Alloys on Selected Functional Properties

Archives of Foundry Engineering, 2014
The cast alloys crystallizing in Fe-C-V system are classified as white cast iron, because all the carbon is bound in vanadium carbides. High vanadium cast iron has a very high abrasion resistance due to hard VC vanadium carbides.
Kawalec M., Kozana J.
doaj   +1 more source

猫科动物冠状病毒感染情况调查及其基因的进化分析

野生动物学报, 2021
为了解冠状病毒在猫科动物的感染情况，对采自上海某动物园的猫科动物144份样品进行检测，并对获得的阳性样品进行扩增和测序。结果显示：SARSCoV2荧光RTPCR检测全部为阴性；FCoV荧光RTPCR检测阳性3份。测序结果显示，检测到FCoV的ORF3、ORF7和S基因均呈遗传多样性，序列存在很大的个体间差异。3a、3b和3c基因主要表现为氨基酸突变。7a基因在第9位（F）、12位（V）和47位（S）均未发生氨基酸替换。它们均具有完整的7b基因。S基因的S1/S2裂解位点处有连续的RRS/A ...
杨德全鞠厚斌朱九超葛菲菲杨显超李鑫沈海潇赵洪进 王建
doaj  

Segmental fECV measurement using PCD-CT as an early predictor of liver function decline in chronic liver disease

Abdominal Radiology
Abstract Purpose The aim of this study was to investigate the utility of segmental hepatic extracellular volume fractions (fECV) calculated using a photon-counting detector CT (PCD-CT) for predicting liver function decline, as reflected by the modified albumin-bilirubin (mALBI) grade in chronic
Takashi Ohtani, Masato Shimada, Kouki Takahashi, Sayuri Hakoda, Yukihiro Tomita, Kiyotaka Takeuchi, Satomi Kanai, Tasuku Wakabayashi, Ayaki Kitano, Kenji Takata, Toshiki Tateishi, Tetsuya Tsujikawa   +11 more
openaire   +1 more source

Sensitivity and specificity of a real-time reverse transcriptase polymerase chain reaction detecting feline coronavirus mutations in effusion and serum/plasma of cats to diagnose feline infectious peritonitis

BMC Veterinary Research, 2017
Background Feline coronavirus (FCoV) exists as two pathotypes, and FCoV spike gene mutations are considered responsible for the pathotypic switch in feline infectious peritonitis (FIP) pathogenesis.
Sandra Felten, Christian M. Leutenegger, Hans-Joerg Balzer, Nikola Pantchev, Kaspar Matiasek, Gerhard Wess, Herman Egberink, Katrin Hartmann   +7 more
doaj   +1 more source

A pre- and during Pandemic Survey of Sars-Cov-2 Infection in Stray Colony and Shelter Cats from a High Endemic Area of Northern Italy

Viruses, 2021
Cats are susceptible to infection with severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2). Whilst a number of studies have been performed worldwide on owned cats, limited data are available on stray, colony or shelter cats. We investigated SARS-
Eva Spada, Fabrizio Vitale, Federica Bruno, Germano Castelli, Stefano Reale, Roberta Perego, Luciana Baggiani, Daniela Proverbio   +7 more
doaj   +1 more source