Results 121 to 130 of about 74,171 (258)

Reprogramming Antitumor Immunity: NK Cell Strategies to Navigate the Immunosuppressive Tumor Microenvironment

Advanced Science, EarlyView.
ABSTRACT Tumor immune escape is a major barrier to durable cancer immunotherapy, as advanced malignancies create a tumor microenvironment (TME) that preferentially exhausts and disables T cell responses. While most approved cell therapies are T cell‐based, this limitation motivates the exploration of an alternative effector cell platform.
Tereza Kochs, Pranay Nath, Alice Chen, Rizwan Romee, Andreia Maia   +4 more
wiley   +1 more source

Evaluation of H₂ supplementation in <i>in situ</i> biomethanation using fed-batch reactors for paper industry wastewater treatment. [PDF]

Front Microbiol
Rodrigues CV, Bonatelli ML, Thattil AM, Amâncio Varesche MB, Nikolausz M.   +4 more
europepmc   +1 more source

Self‐Powered Bearing Sensing and Real‐Time Fault Diagnosis Enabled by Non‐Invasive Triboelectric Sensors and Edge AI Acceleration

Advanced Science, EarlyView.
This study achieves the synergistic integration of self‐powered sensing and edge AI acceleration to establish a real‐time fault diagnosis system. The proposed TENG‐based self‐powered bearing sensor (NSE‐TBS) and FPGA‐accelerated edge AI framework fundamentally break through the inherent limitations of conventional monitoring systems, including complex ...
Kehui Zhu, Zhongheng Liu, Xinming Li, Jinrui Zhang, Meng Li, Yiming Guo, Lihua Han, Yanxue Wang   +7 more
wiley   +1 more source

Viable cell density as an indicator for dynamic feeding strategy in fed-batch and perfusion CHO cell culture. [PDF]

Sci Rep
Kikuchi T, Ohira S, Yamaguchi H.
europepmc   +1 more source

Environmental Insights and Sustainability Opportunities for Scaled‐Up MXene Production Without Etching

Advanced Science, EarlyView.
Through a systematic and comprehensive analysis of the environmental impacts for the emerging MXene synthesis pathways, this study presents process transformation and optimization opportunities for low‐carbon MXene production from laboratory to industrial scales.
Yushuai Huang, Peng Peng, Maoqiao Xiang, Fen Yue, Jiangyan Wang, Wenwei Liu, Qingshan Zhu   +6 more
wiley   +1 more source

Impact of keto leucine and isoleucine on CHO cell central carbon metabolism and performance in fed-batch and steady-state perfusion. [PDF]

Front Bioeng Biotechnol
Reifenberg P, Benjamin D, Le Mignon M, Zimmer A.   +3 more
europepmc   +1 more source

Adapted feeding strategies in fed-batch fermentation improve sugar delivery and ethanol productivity. [PDF]

Bioengineered, 2023
Hung YR, Chae M, Sauvageau D, Bressler DC.   +3 more
europepmc   +1 more source

Revisiting Target‐Aware de novo Molecular Generation with TarPass: Between Rational Design and Texas Sharpshooter

Advanced Science, EarlyView.
TarPass provides a rigorous benchmark for target‐aware de novo molecular generation by jointly evaluating protein‐ligand interactions, molecular plausibility, and drug‐likeness on 18 well‐studied targets. Results show that current models often fail to consistently surpass random baseline in target‐specific enrichment, while post hoc multi‐tier virtual ...
Rui Qin, Zijie Chen, Yurong Li, Meijing Fang, Longji Shen, Yilong Su, Odin Zhang, Qinghan Wang, Qun Su, Jike Wang, Tingjun Hou, Yu Kang   +11 more
wiley   +1 more source

Production of a Dulaglutide Analogue by Apoptosis-Resistant Chinese Hamster Ovary Cells in a 3-Week Fed-Batch Process. [PDF]

Pharmaceuticals (Basel)
Shaifutdinov RR, Sinegubova MV, Vorobiev II, Prokhorova PE, Podkorytov AB, Orlova NA.   +5 more
europepmc   +1 more source

Data‐Driven Modeling of Composition–Processing–Microstructure Relations for Recycled Aluminum Cast Alloys

Advanced Science, EarlyView.
Interpretable machine learning reveals how composition and processing govern the formation and microstructural burden of Fe‐rich intermetallic compounds in recycled Al–Si–Fe–Mn alloys. By separating morphology selection from morphology‐conditioned burden partitioning, this framework shows that identical Fe contents can yield different intermetallic ...
Jaemin Wang, Waleed Mohammed, Dierk Raabe   +2 more
wiley   +1 more source