Results 1 to 10 of about 88,820 (301)

Control of fed-batch fermentations

open access: yesBiotechnology Advances, 1999
Fed-batch fermentation is used to prevent or reduce substrate-associated growth inhibition by controlling nutrient supply. Here we review the advances in control of fed-batch fermentations. Simple exponential feeding and inferential methods are examined,
Sang Yup Lee   +2 more
exaly   +8 more sources

Comparison Between Simple Batch and Fed-Batch Bioreactor Cultivation of Recombinant BCG [PDF]

open access: yesPharmaceutics
Background/Objectives: Tuberculosis continues to be a significant global health concern, causing 1.3 million deaths in 2022, particularly affecting children under 5 years old.
Sarah Mendes   +6 more
doaj   +3 more sources

Fed-batch bioreactor modeling

open access: yesSoftwareX
This paper describes an open-source computational tool developed for the modeling and simulation of fed-batch bioreactors, particularly for processes employing Chinese Hamster Ovary (CHO) cells, which are integral to biopharmaceutical manufacturing.
Tilen Gimpelj, Aleksandar Tošić
doaj   +3 more sources

Transferability of bioprocessing modes for recombinant protease production: from fed-batch to continuous cultivation with Bacillus licheniformis [PDF]

open access: yesBMC Biotechnology
Background Proteases are essential in various industries due to their unique substrate specificities and robustness in different operational conditions.
Stefan Kittler   +7 more
doaj   +2 more sources

Batch and Fed-Batch Fermentation System on Ethanol Production from Whey using Kluyveromyces marxianus

open access: yesInternational Journal of Renewable Energy Development, 2013
Nowadays reserve of fossil fuel has gradually depleted. This condition forces many researchers to  find energy alternatives which is renewable and sustainable in the future.
H Hadiyanto   +3 more
doaj   +3 more sources

Batch-to-Batch Iterative Learning Control of a Fed-Batch Fermentation Process

open access: yesChemistry and Materials Research, 2022
In this work, Iterative Learning Control on a fed-batch fermentation process using linearised models has been studied. The repetitive nature of batch processes enables ILC to obtain information from a previous batch in order to improve the performance of
Okoro, Franklin, Okoli, Nwamaka Linda
core   +2 more sources

Feed optimization in fed-batch culture

open access: yes, 2014
Fed-batch processes are a current preference for the production of recombinant proteins in mammalian cells. The use of nutrient feeding prevents the depletion of important medium components, and results in improved culture longevity and high cell and ...
Henriques, Mariana   +4 more
core   +4 more sources

Model structures for batch and fed-batch ethanol fermentations

open access: yes2019 IEEE CHILEAN Conference on Electrical, Electronics Engineering, Information and Communication Technologies (CHILECON), 2019
Parameter estimation is one of the most challenging steps while modelling a biological process, due to the inherent complexity of this type of processes and the difficulty in obtaining reliable experimental data.
Serebrinsky Duek, Kineret Rivka   +3 more
core   +2 more sources

Optimization of Culture Media and Feeding Strategy for High Titer Production of an Adenoviral Vector in HEK 293 Fed-Batch Culture [PDF]

open access: yesVaccines
Adenoviruses are efficient and safe vectors for delivering target antigens and adenovirus-based vaccines have been used against a wide variety of pathogens, including tuberculosis and COVID-19.
Chun Fang Shen   +4 more
doaj   +2 more sources

Analysis of biomass productivity and physiology of Nitrososphaera viennensis grown in continuous culture

open access: yesFrontiers in Microbiology, 2023
Microbial ammonia oxidation is the first and usually rate limiting step in nitrification and is therefore an important step in the global nitrogen cycle. Ammonia-oxidizing archaea (AOA) play an important role in nitrification.
Michael Melcher   +6 more
doaj   +1 more source

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