Optimization of Culture Media and Feeding Strategy for High Titer Production of an Adenoviral Vector in HEK 293 Fed-Batch Culture [PDF]
VaccinesAdenoviruses are efficient and safe vectors for delivering target antigens and adenovirus-based vaccines have been used against a wide variety of pathogens, including tuberculosis and COVID-19.
Chun Fang Shen +4 more
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CONVERSION OF PINEAPPLE JUICE WASTE INTO LACTIC ACID IN BATCH AND FED – BATCH FERMENTATION SYSTEMS [PDF]
Reaktor, 2008 Pineapple juice waste contains valuable components, which are mainly sucrose, glucose, and fructose. Recently, lactic acid has been considered to be an important raw material for the production of biodegradable lactide polymer.
Abdullah Mochamad Busairi
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A Single Dynamic Metabolic Model Can Describe mAb Producing CHO Cell Batch and Fed-Batch Cultures on Different Culture Media. [PDF]
PLoS ONE, 2015 CHO cell culture high productivity relies on optimized culture medium management under fed-batch or perfused chemostat strategies enabling high cell densities.
Julien Robitaille +2 more
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Double-stranded RNA production and the kinetics of recombinant Escherichia coli HT115 in fed-batch culture [PDF]
Biotechnology Reports, 2018 Double-stranded RNA can induce interference processes. The specificity of this system raises the possibility of using dsRNA for therapeutic applications targeting viral diseases. Escherichia coli HT115 (DE3) has been widely used to produce dsRNA; however,
Ljubomir Papić +3 more
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Application of different feeding strategies in fed batch culture for pullulanase production using sago starch [PDF]
Carbohydrate Polymers, 2014 The production of pullulanase by Bacillus flavothermus KWF-1 in batch and fed batch culture were compared using 2 L bioreactor. In batch culture, 0.0803 U/mL of pullulanase activity with specific activity of 0.0213 U/mg was produced by controlling the ...
Mohamad, Shaza Eva +9 more
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In vitro growth of Curcuma longa L. in response to five mineral elements and plant density in fed-batch culture systems. [PDF]
PLoS ONE, 2015 Plant density was varied with P, Ca, Mg, and KNO3 in a multifactor experiment to improve Curcuma longa L. micropropagation, biomass and microrhizome development in fed-batch liquid culture. The experiment had two paired D-optimal designs, testing sucrose
Rabia F El-Hawaz +2 more
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Progress in fed-batch culture for recombinant protein production in CHO cells [PDF]
Applied Microbiology and Biotechnology, 2023 Chun-Liu Mi +2 more
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Enzyme and Microbial Technology, 1997 A mixotrophic culture might be used as an alternative to conventional photoautotrophic mass culture systems for production of high value chemicals and pharmaceutical by Spirulina platensis.
Feng Chen +3 more
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Viable cell density as an indicator for dynamic feeding strategy in fed-batch and perfusion CHO cell culture [PDF]
Scientific ReportsThe general approach to industrial production of monoclonal antibodies is fed-batch culture using Chinese Hamster Ovary (CHO) cells. Perfusion culture is also attracting attention as a next-generation culture method.
Takuya Kikuchi +2 more
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Process-Driven Acetate-Based Lipid Production by the Oleaginous Yeast Lipomyces starkeyi [PDF]
MicroorganismsOleaginous yeasts are promising microbial platforms for lipid production from non-conventional carbon sources; however, acetate utilization is frequently constrained by physiological limitations associated with culture pH.
Akihiro Ishioka +5 more
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