Results 111 to 120 of about 53,182 (300)

tBid‐Mediated Genetic Ablation of Connective Tissue Cells Reveals Their Key Regulatory Function During Limb Regeneration in Axolotls

open access: yesAdvanced Science, EarlyView.
We establish a tBid‐mediated cell ablation system in axolotls, achieve rapid and efficient ablation of multiple cell types, including muscle stem cell, spinal cord cell, and connective tissue (CT) cells. We investigate the role of CT using tBid‐mediated CT ablation and identify its essential role for limb development and regeneration.
Yan Hu   +11 more
wiley   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

open access: yesAdvanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li   +7 more
wiley   +1 more source

Production of toluene cis-glycol using recombinant Escherichia coli strains in glucose-limited fed batch culture

open access: yes, 1999
Production of toluene cis-glycol (TCG) was investigated using recombinant Escherichia coli strains that express toluene dioxygenase under the tac promoter. E.
Phumathon, Pongsuda   +3 more
core   +1 more source

Materials‐Guided Gene‐Ionizable Lipid Nanoparticles to Reverse Iron‐Associated Immune Resistance in Renal Cancer

open access: yesAdvanced Science, EarlyView.
ABSTRACT Iron overload is a common metabolic disturbance in cancer and contributes to poor outcomes in renal cell carcinoma (RCC), yet its effects on the tumour immune microenvironment remain unclear. Here we identify a previously unrecognized immunosuppressive axis in which iron overload downregulates the palmitoyltransferase ZDHHC12 in CD8+ T cells ...
Xin Jin   +16 more
wiley   +1 more source

Intensification of lovastatin biosynthesis with the use of lactose and glycerol as carbon sources in a batch and in discontinuous fed-batch and continuous fed-batch culture

open access: yes, 2012
W pracy została przedstawiona strategia maksymalizacji biosyntezy lowastatyny przez Aspergillus terreus ATCC 20542 przy jednoczesnym użyciu laktozy i glicerolu jako źródeł węgla w procesach okresowych jak i półciągłych.
Pawlak, M., Bizukojć, M.
core  

Ammonia Inhibition Hybridomas Propagated in Batch, Fed-Batch, and Continuous-Culture

open access: yes, 1994
The nature and temporal development of ammonia inhibition were investigated in batch, fed-batch, and continuous cultures. Significant inhibition was observed when cells were inoculated in serum-containing or chemically defined medium containing more than
Greenfield, PF   +7 more
core   +1 more source

Small-scale shaken bioreactors for fed-batch cultivation with parallel online monitoring

open access: yes, 2020
Small-scale shaken bioreactors, such as shake flasks and microtiter plates, are the most frequently used reactor systems during initial bioprocess development. Originally, they were designed to be operated in batch mode.
Habicher, Tobias
core   +1 more source

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