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Enzymatic production of lactulose by fed-batch and repeated fed-batch reactor

Bioresource Technology, 2021
The effects of the most significant operational variables on reactor performance of fed-batch and repeated fed-batch were evaluated in the lactulose production by enzymatic transgalactosylation. Feed flowrate in the fed stage (F) and fructose to lactose molar ratio (Fr/L) were the variables that mostly affected the values ​​of lactulose yield (YLu ...
Carla Aburto   +2 more
exaly   +3 more sources

Fed-batch culture technology

Biotechnology Advances, 1986
The use of fed-batch procedures offers distinct advantages over other modes of operation of bioreactors, and is a widely researched technique. These advantages are discussed; some uses of fed-batch procedures and the associated methods of modelling and control are reviewed.
B J, Minihane, D E, Brown
exaly   +3 more sources

Batch, fed-batch and repeated fed-batch fermentation processes of the marine thraustochytrid Schizochytrium sp. for producing docosahexaenoic acid

Bioprocess and Biosystems Engineering, 2013
Different fermentation processes, including batch, fed-batch and repeated fed-batch processes by Schizochytrium sp., were studied and compared for the effective DHA-rich microbial lipids production. The comparison between different fermentation processes showed that fed-batch process was a more efficient cultivation strategy than the batch process ...
Lu-Jing Ren, Xiao-Jun Ji, Zhi-Kui Nie
exaly   +3 more sources

Batch and Fed‐Batch Degradation of Enrofloxacin by the Fenton Process

Chemical Engineering & Technology, 2017
AbstractEnrofloxacin is a synthetic second‐generation fluoroquinolone used as an antimicrobial agent exclusively in veterinary medicine. To simulate the treatment of wastewater contaminated by enrofloxacin, four‐day long fed‐batch runs were carried out according to the Fenton process with an enrofloxacin solution as model, to which hydrogen peroxide ...
Frade, Verônica M. F.   +4 more
openaire   +2 more sources

Dynamic reoptimization of a fed‐batch fermentor

Biotechnology and Bioengineering, 1999
Traditionally, fed-batch biochemical process optimization and control use complicated models and off-line optimizers with no on-line model adaptation and re-optimization. This work demonstrates the applicability, effectiveness, and economic potential, of a simple phenomenological model for modeling, and a novel optimizer for on-line re-optimization and
M S, Iyer, T F, Wiesner, R R, Rhinehart
openaire   +2 more sources

Fed-batch bioproduction of spectinomycin

2007
Actinomycetes produce about 67% of the known antibiotics covering a wide range of chemical structures. However, their filamentous growth present several problems during industrial processes. Among these problems oxygen transfer limitation is critical.
J, Gomes, A S, Menawat
openaire   +2 more sources

Calorimetric control of fed‐batch fermentations

Biotechnology and Bioengineering, 1990
AbstractMeasurements of the heat produced by Saccharomyces cerevisiae CBS 426 were used in conjunction with elemental and enthalpic balances to control fed‐batch fermentations. A proportional control using the ratio of carbon dioxide evolution rate to heat production resulted in high biomass yields and minimal ethanol production.
Randolph TW   +3 more
openaire   +3 more sources

Feedback optimization of fed‐batch fermentation

Biotechnology and Bioengineering, 1987
AbstractThe problem of feedback optimization of the feed rate for fed‐batch fermentation processes is formulated in the framework of singular control theory and switching hypersurfaces. Using four differential balance equations that describe a general class of fedbatch processes and a general objective function to be minimized, it is shown that under ...
J M, Modak, H C, Lim
openaire   +2 more sources

Fed-batch versus batch fermentation

Bioprocess Engineering, 1994
This article concerns the comparison between batch and fed-batch fermentation based on productivity and including the analysis of the implications on product manufacturing cost.
openaire   +1 more source

Fed-batch cultivation of Wautersia eutropha

Bioresource Technology, 2008
Batch kinetics of polyhydroxybutyrate (PHB) synthesis in a bioreactor under controlled conditions of pH and dissolved oxygen gave a biomass of 14 g l(-1) with a PHB concentration of 6.1 g l(-1) in 60 h. The data of the batch kinetics was used to develop a mathematical model, which was then extrapolated to fed-batch by incorporating the dilution due to ...
Pallavi, Patwardhan, Ashok K, Srivastava
openaire   +2 more sources

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