Results 81 to 90 of about 88,820 (301)

Functional State Modelling of Cultivation Processes: Dissolved Oxygen Limitation State [PDF]

International Journal Bioautomation, 2015
A new functional state, namely dissolved oxygen limitation state for both bacteria Escherichia coli and yeast Saccharomyces cerevisiae fed-batch cultivation processes is presented in this study.
Olympia Roeva, Tania Pencheva, Stoyan Tzonkov, Bernd Hitzmann   +3 more
doaj   +2 more sources

Packed Hydrogel Microfibers as Scaffolds Supporting Dynamic Cellular Behavior and Biomaterial Inks in 3D Printing

Advanced Healthcare Materials, EarlyView.
Packed hydrogel microfiber (PHM) materials consist of flexible and high aspect ratio hydrogel components that, as a bulk material, are simultaneously mechanically robust and dynamic. Cells cultured in or on PHM scaffolds can be influenced by topographical cues or interact with a dynamic environment that permits cell spreading and multicellular ...
M. Gregory Grewal, Remington M. Martinez, Georgia T. Helein, Montserrath G. Ibarra Rivera, Rodolfo Martinez Jr., Jenna L. Sumey, Steven R. Caliari, Christopher B. Highley   +7 more
wiley   +1 more source

Development of a Synthetic Hydrogel to Foster Microvascularization of an Endometriosis Microphysiological System

Advanced Healthcare Materials, EarlyView.
ABSTRACT The ascent of novel alternative methods in drug development spotlights the dual needs for improved biological fidelity to in vivo, along with reproducibility, especially in regulatory applications. The need for pre‐clinical models of patient‐derived endometriosis lesions motivates the development of a vascularizable, completely synthetic ...
Lauren Pruett, Laura Bahlmann, Ryan Ogi, Angela Jiao, Priyatanu Roy, Matthew Johnson, David Trumper, Linda Griffith   +7 more
wiley   +1 more source

Universal Capacitance Model for Real-Time Biomass in Cell Culture

Sensors, 2015
Capacitance probes have the potential to revolutionize bioprocess control due to their safe and robust use and ability to detect even the smallest capacitors in the form of biological cells. Several techniques have evolved to model biomass statistically,
Viktor Konakovsky, Ali Civan Yagtu, Christoph Clemens, Markus Michael Müller, Martina Berger, Stefan Schlatter, Christoph Herwig   +6 more
doaj   +1 more source

Design of an optimised fed-batch process for insulin precursor production in Pichia pastoris

, 2011
Includes bibliographical references (leaves 98-103).The increasing prevalence of diabetes worldwide has greatly increased the demand for insulin, a key type of treatment for many diabetics.
Bhardwaj, Vinayak
core  

Uso de um sensor de compostos volateis para o controle de uma fermentação batelada alimentada de Sacharomyces cerevisiae [PDF]

, 1995
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro TecnologicoO trabalho visa a maximização da produção de Saccharomyces cerevisiae, em um processo fed-batch, fazendo o controle do etanol produzido na fermentação.
Oliveira, Débora de
core  

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Epidermal Patch Technologies for Integrated Healthcare and Infection Management

Advanced Healthcare Materials, EarlyView.
Epidermal patches have evolved from simple wound coverings into multifunctional, skin‐conformable platforms integrating drug delivery, biosensing, and therapeutic functionalities. This review highlights their material innovations, fabrication strategies, and intelligent designs, including hydrogels, microneedles, and flexible electronics, while ...
Yuqi Wang, Atakan Tevlek, Pawel L. Urban, Boaz Mizrahi, Onome Ejeromedoghene, Roshan Deen, Yuanjing Lin, Jagan Mohan Dodda   +7 more
wiley   +1 more source

Microgel‐Based 3D Bioprinting: A Convergent Strategy Integrating Material Design, Jamming Dynamics, and Biological Function

Advanced Healthcare Materials, EarlyView.
Microgel‐based 3D printed constructs represent a compelling and versatile innovation for engineering architecturally complex, dynamically remodelable, and biocompatible structures with high structural fidelity and bioactivity. By integrating material design, biofabrication, and biological function, these systems enable the development of adaptive ...
Elena Ghighină, Andreea Ioana Dinu, Jana Ghițman   +2 more
wiley   +1 more source

Mixed‐Metal Promotion in a Manganese‐Molybdenum Oxynitride as Catalyst to Integrate C─C and C─N Coupling Reactions for the Direct Synthesis of Acetonitrile from Syngas and Ammonia

Advanced Materials, EarlyView.
Transition metal oxy/carbo‐nitrides show great promise as catalysts for sustainable processes. A Mn‐Mo mixed‐metal oxynitride attains remarkable performance for the direct synthesis of acetonitrile, an important commodity chemical, via sequential C─N and C─C coupling from syngas (C1) and ammonia (N1) feedstocks.
M. Elena Martínez‐Monje, Wilson Henao, Tania Rodenas, Patricia Concepción, Virginia Pérez Dieste, Alexander Missyul, Giovanni Agostini, Gonzalo Prieto   +7 more
wiley   +1 more source