Results 51 to 60 of about 5,560,090 (288)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

The Strategic Competitive Advantages Forming Investment Appeal of the Far East Federal District

Управленческое консультирование, 2018
In article the strategic competitive advantages forming investment appeal of the Far East federal district are revealed. Major factors the districts influencing investment activity in Far East federal are revealed.
Airat Farucovich Yarhamov
doaj  

Analysis of Epizootiological-Epidemiological Situation on Brucellosis in the Russian Federation in 2018 and Forecast for 2019

Проблемы особо опасных инфекций, 2019
Presented is the analysis of brucellosis incidence among humans and animals in the Russian Federation in 2018. Epizootiological situation in the regions of developed animal husbandry remains reasonably tense.
D. G. Ponomarenko, E. B. Ezhlova, D. V. Rusanova, A. A. Khachaturova, N. D. Pakskina, T. V. Berdnikova, E. A. Manin, O. V. Semenko, O. V. Logvinenko, E. L. Rakitina, M. V. Kostyuchenko, O. V. Maletskaya, A. N. Кulichenko   +12 more
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Phylogeny and Biological Properties of Brucella abortus Strains Isolated in the Volga and Central Federal Districts in 2017–2024

Проблемы особо опасных инфекций
The aim of the work was to study biological, molecular-genetic properties and to determin the phylogenetic affiliation of Brucella abortus strains isolated in the Volga and Central Federal Districts.Materials and methods.
D. A. Kovalev, S. V. Pisarenko, I. V. Kuznetsova, V. I. Kolomytseva, D. G. Ponomarenko, N. A. Shapakov, A. A. Khachaturova, N. S. Safonova   +7 more
doaj   +1 more source

Evolution characteristics of temporal and spatial pattern of Russian economic differences since the 21st century.

PLoS ONE, 2022
Under the background of "the Belt and Road" and "the economic corridor of China, Mongolia and Russia" initiatives, it is of great significance to study the temporal and spatial economic pattern in the Russian Federation. Based on the economic development
Nan-Chen Chu, Ping-Yu Zhang, Xiang-Li Wu
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Analysis of the Epizootiological and Epidemiological Situation on Tularemia in the Territory of the Russian Federation in 2023 and Forecast for 2024

Проблемы особо опасных инфекций
In 2023, 305 cases of human infection with tularemia agent were registered in the Russian Federation. Epizootic manifestations of the infection, varying in the degree of intensity, were identified in 65 constituent entities of the country, and sporadic ...
T. Yu. Kudryavtseva, V. P. Popov, A. N. Mokrievich, E. S. Kulikalova, A. V. Kholin, A. V. Mazepa, M. A. Borzenko, E. A. Cherepanova, V. A. Matveeva, D. V. Trankvilevsky, M. V. Khramov, I. A. Dyatlov   +11 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source