Results 11 to 20 of about 35,060 (232)

A coherent FOXO3-SNAI2 feed-forward loop in autophagy. [PDF]

open access: yesProc Natl Acad Sci U S A, 2022
Significance Understanding autophagy regulation is instrumental in developing therapeutic interventions for autophagy-associated disease. Here, we identified SNAI2 as a regulator of autophagy from a genome-wide screen in HeLa cells.
Guo X   +12 more
europepmc   +3 more sources

Noise characteristics of feed forward loops [PDF]

open access: yesPhysical Biology, 2005
A prominent feature of gene transcription regulatory networks is the presence in large numbers of motifs, i.e, patterns of interconnection, in the networks. One such motif is the feed forward loop (FFL) consisting of three genes X, Y and Z. The protein product of x of X controls the synthesis of protein product y of Y. Proteins x and y jointly regulate
Ghosh, Bhaswar   +2 more
openaire   +3 more sources

Implications of the HDAC6-ERK1 feed-forward loop in immunotherapy. [PDF]

open access: yesJ Immunol Sci, 2018
The oncogene HDAC6 controls numerous cell processes that are related to tumorigenesis and metastasis, and has recently arisen as a target to treat malignancies. The ERK cascade is a classic pathway driving oncogenesis, and the components of this pathway are either highly mutated in cancers or are vital in cancer's pathological activity.
Wu JY, Moses N, Bai W, Zhang XM.
europepmc   +4 more sources

MicroRNA-regulated feed forward loop network [PDF]

open access: yesCell Cycle, 2009
Comment on: Cohen EE, et al. A feed-forward loop involving protein kinase Calpha and microRNAs regulates tumor cell cycle. Cancer Res 2009; 69:65-74.
Ezra E W, Cohen, Marsha Rich, Rosner
openaire   +2 more sources

Behavioural variation among workers promotes feed-forward loops in a simulated insect colony

open access: yesRoyal Society Open Science, 2022
Coordinated responses in eusocial insect colonies arise from worker interaction networks that enable collective processing of ecologically relevant information. Previous studies have detected a structural motif in these networks known as the feed-forward
Carrie Easter   +2 more
doaj   +1 more source

Methane Number Control of Fuel Gas Supply System Using Combined Cascade/Feed-Forward Control

open access: yesJournal of Marine Science and Engineering, 2020
Liquefied natural gas began to attract attention as a ship fuel to reduce environmental pollution and increase energy efficiency. During this period, highly efficient internal combustion engines emerged as the new propulsion system instead of steam ...
Soon-kyu Hwang, Byung-gun Jung
doaj   +1 more source

Inferring links in directed complex networks through feed forward loop motifs

open access: yesHumanities & Social Sciences Communications, 2023
Complex networks are mathematical abstractions of real-world systems using sets of nodes and edges representing the entities and their interactions.
Satyaki Roy   +2 more
doaj   +1 more source

Motif Participation by Genes in E. coli Transcriptional Networks

open access: yesFrontiers in Physiology, 2012
Motifs are patterns of recurring connections among the genes of genetic networks that occur more frequently than would be expected from randomized networks with the same degree sequence.
Michael eMayo   +3 more
doaj   +1 more source

Abundance of connected motifs in transcriptional networks, a case study using random forests regression

open access: yesEAI Endorsed Transactions on Mobile Communications and Applications, 2016
Biological network topologies are known to be robust despite internal and external perturbances. Motifs such as feed-forward loop and bifan have been marked to contribute to structural and functional significance.
Syed Khajamoinuddin   +4 more
doaj   +1 more source

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