Results 81 to 90 of about 165,251 (363)

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane, Giorgia Coratti, Chiara Cutrì, Antonio Varone, Riccardo Masson, Adele D'Amico, Valeria Sansone, Sonia Messina, Federica Ricci, Chiara Ticci, Claudio Bruno, Caterina Agosto, Francesca Benedetti, Antonella Pini, Sabrina Siliquini, Massimiliano Filosto, Alberto Zambon, Ilaria Bitetti, Maria Rosaria Manna, Claudia Dosi, Riccardo Zanin, Stefano Parravicini, Roberto De Sanctis, Giulia Stanca, Michela Catteruccia, Michele Tosi, Irene Mizzoni, Emilio Albamonte, Valentina Franchino, Maria Sframeli, Ilaria Cavallina, Elena Procopio, Michele Sacchini, Simone Morando, Noemi Brolatti, Federica Trucco, Gaia Scarpini, Elena Briganti, Beatrice Berti, Concetta Palermo, Daniela Leone, Stefano C. Previtali, Eugenio Mercuri, the ITASMAC working group   +43 more
wiley   +1 more source

Morphofunctional evaluation of laboratory animals' organism for studying the toxicity parameters of a combined antibacterial drug

Науковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Ґжицького: Серія Ветеринарні науки
The article presents the results of studying the acute and subacute toxicity parameters of the new combined two-component antimicrobial veterinary drug “Riketron H” (solution for injection).
M. Zhyla, O. Pyatnychko, Yu. Stronskyi, N. Shkodyak, M. Shkil, N. Lisova, O. Sobodosh, I. Patareha, O. Poklad   +8 more
doaj   +1 more source

Estimation of efficiency of application of technological feed supplement of hepasorbex in vitro

Науковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Гжицького. Серія: Сільськогосподарські науки, 2019
The study of the effectiveness of the application of the technological feed additive Hepasorbex from the functional group of substance in order to reduce the contamination of feed with mycotoxins in laboratory conditions has been carried out.
T. R. Levytskyy
doaj   +1 more source

Processing peracetic acid treated bloodmeal into bioplastic [PDF]

, 2012
Renewable and biodegradable bioplastics can be produced from biopolymers such as proteins. Animal blood is a by-product from meat processing and is rich in protein. It is dried into low value bloodmeal and is used as animal feed or fertiliser.
Lay, Mark C., Low, Aaron, Verbeek, Casparus Johan R.   +2 more
core   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez, Monica Ferrer Socorro, Kathryn Yang, Nicole Battaglia, Zainab Zaman, Mariko Bennett, Adeline Vanderver, Pui Y. Lee, Lauren A. Henderson, Milena M. Andzelm, Darius Ebrahimi‐Fakhari   +10 more
wiley   +1 more source

Evaluation of efficacy of a drug based on fipronil, ivermectin, and pyriproxyfen against ecto- and endoparasitic invasions of dogs and cats

Regulatory Mechanisms in Biosystems
Ecto- and endoparasitic invasions of dogs and cats are treated using drugs based on fipronil, ivermectin, and pyriproxyfen. That is why our objective was performing a field study to measure the efficacy of a complex drug with different mechanisms of the ...
I. D. Yuskiv, O. L. Tishyn, L. L. Yuskiv   +2 more
doaj   +1 more source

Evaluation criteria for including feed materials in Annex II C and dietary supplements in Annex II D of the EC-Regulation 2092/91 [PDF]

, 2006
Organic livestock farming is intended to contribute to the equilibrium of agricultural production systems; establish and maintaining an interdependence between soils, plants and animals; is land-related ruling out landless productions, and should support
Padel, S., Sundrum, A.
core  

Negligible effects of tryptophan on the aflatoxin adsorption of sodium bentonite [PDF]

, 2014
The main objective of this study was to determine if the competitive adsorption of tryptophan (Trp) and aflatoxin B1 (AFB1) could potentially affect the ability of a sodium bentonite (NaB) to prevent aflatoxicosis in monogastric animals.
Chiacchiera, Stella Maris, Copia, P., Dalcero, Ana Maria, Magnoli, Alejandra Paola, Magnoli, Carina Elizabeth, Monge, Maria del Pilar   +5 more
core   +1 more source

What Do Large Language Models Know About Materials?

Advanced Engineering Materials, EarlyView.
If large language models (LLMs) are to be used inside the material discovery and engineering process, they must be benchmarked for the accurateness of intrinsic material knowledge. The current work introduces 1) a reasoning process through the processing–structure–property–performance chain and 2) a tool for benchmarking knowledge of LLMs concerning ...
Adrian Ehrenhofer, Thomas Wallmersperger, Gianaurelio Cuniberti   +2 more
wiley   +1 more source