Results 81 to 90 of about 750,358 (301)

Crosstalk Between Brain-Derived Neurotrophic Factor And N-Methyl-D-Aspartate Receptor Signaling In Neurons [PDF]

, 2008
Glutamate is the major excitatory neurotransmitter in brain exerting prosurvival effect on neurons via N-methyl-D-aspartate receptor (NMDAR) signaling under physiological conditions.
Georgiev, Danko, Kambe, Yuki, Taniura, Hideo, Yoneda, Yukio   +3 more
core  

Interactions between visceral afferent signaling and stimulus processing [PDF]

, 2015
Visceral afferent signals to the brain influence thoughts, feelings and behaviour. Here we highlight the findings of a set of empirical investigations in humans concerning body-mind interaction that focus on how feedback from states of autonomic arousal ...
Anderson, Barrett, Bechara, Bechara, Boubela, Cannon, Cannon, Cantril, Clark, Critchley, Critchley, Critchley, Critchley, Critchley, Critchley, Critchley, Damasio, Damasio, Darwin, Donadio, Donadio, Dworkin, Edwards, Ekman, Ekman, Ekman, Feinstein, Garfinkel, Garfinkel, Gianaros, Gray, Gray, Gray, Gray, Gray, Hugo D. Critchley, James, Katkin, Katkin, Lacey, Lacey, Lange, Lange, LeDoux, Maranon, McIntyre, McIntyre, Medford, Nagai, Park, Paulus, Paulus, Pollatos, Rau, Santos, Sarah N. Garfinkel, Schachter, Schandry, Wager, Wallin, Whitehead, Wiens, Wild   +62 more
core   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Examining sensory interference and adaptive feedback in VR-based learning for cognitive load management

Computers in Human Behavior Reports
Managing cognitive load is a critical challenge in immersive learning environments, where sensory interference could disrupt attention and information processing.
Jiacheng Sun, Katherine Shagalov, Ting Liao   +2 more
doaj   +1 more source

The Effect of Secret Clock Manipulation on 10 km Cycle Time Trial Performance. [PDF]

, 2010
The anticipatory RPE feedback model (Tucker 2009) proposes that during self paced exercise tasks, muscular work is continually regulated through comparison of a subconscious ‘template’ Rating of Perceived Exertion (RPE) that serves to protect against the
Renfree, Andrew, Thomas, Gavin
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

A Physiological Feedback Controlled Exercise Video Game

, 2012
Purpose: This thesis presents a proof-of-concept for the use of physiological feedback in active video games to control the heart rate of players. Rationale: Physiological feedback controls can be used to increase or decrease the physical demands of an active video game presented to the user.
openaire   +2 more sources

Physiologic Insulin Delivery with Insulin Feedback: A Control Systems Perspective

IFAC proceedings volumes, 2009
Individuals with type 1 diabetes mellitus must effectively manage glycemia to avoid acute and chronic complications related to aberrations of glucose levels. Because optimal diabetes management can be difficult to achieve and burdensome, research into a closed-loop insulin delivery system has been of interest for several decades. This paper provides an
openaire   +2 more sources

Using Virtual Reality to increase technical performance during rowing workouts [PDF]

, 2018
Technology is advancing rapidly in virtual reality (VR) and sensors, gathering feedback from our body and the environment we are interacting in. Combining the two technologies gives us the opportunity to create personalized and reactive immersive ...
Vivo Montero, Ricard
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