Results 31 to 40 of about 1,822,010 (290)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Microwave Frequency Comb Optimization for FMCW Generation Using Period-One Dynamics in Semiconductor Lasers Subject to Dual-Loop Optical Feedback

open access: yesPhotonics
Microwave frequency comb (MFC) optimization for frequency-modulated continuous-wave (FMCW) generation by period-one (P1) dynamics with dual-loop optical feedback are numerically investigated.
Haomiao He   +7 more
doaj   +1 more source

Rhythmic transcription of Bmal1 stabilizes the circadian timekeeping system in mammals

open access: yesNature Communications, 2022
The mammalian circadian clock is composed of clock genes forming transcriptional feedback loops. Here, the authors identify a key role of the secondary feedback loop that is interlocked with the core loop to establish a perturbation-resilient clock ...
Yasuko O. Abe   +8 more
doaj   +1 more source

Feedback Loop [PDF]

open access: yesMechanical Engineering, 2009
This article highlights about young engineers who want early performance feedback on how they are doing their jobs. One difference is that younger engineers believe the feedback should stream to them the same way other digitized information does: instantly and often.
openaire   +1 more source

Data-driven control design for neuroprotheses: a virtual reference feedback tuning (VRFT) approach [PDF]

open access: yes, 2004
This paper deals with design of feedback controllers for knee joint movement of paraplegics using functional electrical stimulation (FES) of the paralyzed quadriceps muscle group.
F. Previdi   +16 more
core   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Research on Vibration Suppression Method Based on Double Loop Position Feedback Control

open access: yesSensors
Aiming at the problem that the position control accuracy of the traditional semi-closed-loop control and the vibration caused by the nonlinear characteristics of the system are easily affected by the full closed-loop control, a double-loop position ...
Yunfei Qu   +4 more
doaj   +1 more source

Learning through feedback loop metaphors [PDF]

open access: yes, 2015
The metaphor of a feedback loop underpinned a significant curriculum change in a first year teacher-education unit. Assessment for Learning (AfL) practices such as discussing examples of previous student work and giving peer feedback were embedded within
Willis, Jill
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Approximately Optimal Control of Nonlinear Dynamic Stochastic Problems with Learning: The OPTCON Algorithm

open access: yesAlgorithms, 2021
OPTCON is an algorithm for the optimal control of nonlinear stochastic systems which is particularly applicable to economic models. It delivers approximate numerical solutions to optimum control (dynamic optimization) problems with a quadratic objective ...
Dmitri Blueschke   +2 more
doaj   +1 more source

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