Results 71 to 80 of about 246,352 (271)

Nutrient conditions determine the strength of herbivore‐mediated stabilizing feedbacks in barrens

open access: yesEcology and Evolution, 2023
Abiotic environmental conditions can significantly influence the way species interact. In particular, plant–herbivore interactions can be substantially dependent on temperature and nutrients. The overall product of these relationships is critical for the
Laia Illa‐López   +13 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Breaking the Ecosystem Balance Over the Tibetan Plateau

open access: yesEarth's Future, 2022
Ecosystem imbalance is often associated with a feedback mechanism, which a self‐amplifying or ‐dampening process expressed by a pathway of causal processes that come back to its starting point, establishing a cycle. Warming, which is increasing worldwide
Dongliang Han   +6 more
doaj   +1 more source

Ecosystems as climate controllers – biotic feedbacks (a review) [PDF]

open access: yes, 2008
There is good evidence that higher global temperature will promote a rise of green house gas levels, implying a positive feedback which will increase the effect of the anthropogenic emissions on global temperatures.
Drégelyi-Kiss, G.   +2 more
core  

Feedbacks from the metabolic network to the genetic network reveal regulatory modules in E. coli and B. subtilis

open access: yes, 2018
The genetic regulatory network (GRN) plays a key role in controlling the response of the cell to changes in the environment. Although the structure of GRNs has been the subject of many studies, their large scale structure in the light of feedbacks from ...
Jain, Sanjay   +2 more
core   +2 more sources

Feedback on feedback – does it work? [PDF]

open access: yesCritical CALL – Proceedings of the 2015 EUROCALL Conference, Padova, Italy, 2015
It is well documented that providing assessment feedback through the medium of screencasts is favourably received by students and encourages deeper engagement with the feedback given by the language teacher. In this short paper the authors will report the results of a case study where students moved from passively receiving feedback to actively ...
Speicher, Oranna, Stollhans, Sascha
openaire   +3 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

AMF, phylogeny, and succession: specificity of response to mycorrhizal fungi increases for late‐successional plants

open access: yesEcosphere, 2016
Arbuscular mycorrhizal (AM) fungal communities are important to plant community productivity and diversity; however, the importance of AM fungal composition to community dynamics remains largely unknown.
Liz Koziol, James D. Bever
doaj   +1 more source

Global Carbon Cycle and Climate Feedbacks in the NASA GISS ModelE2.1

open access: yesJournal of Advances in Modeling Earth Systems, 2020
We present results from the NASA GISS ModelE2.1‐G‐CC Earth System Model with coupled climate‐carbon cycle simulations that were submitted to the sixth phase of the Coupled Model Intercomparison Project (CMIP6) Coupled Climate‐Carbon Cycle MIP (C4MIP ...
Gen Ito   +9 more
doaj   +1 more source

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