Results 81 to 90 of about 12,326 (298)

Perivascular Matrix Densification Dysregulates Angiogenesis and Activates Pro‐Inflammatory Endothelial Cells

Advanced Science, EarlyView.
Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia, William Y. Wang, Kyle A. Jacobs, Kairav Maniar, Daphne Lin, Evan H. Jarman, Daniel L. Matera, Kristen Loesel, Christopher D. Davidson, Harrison L. Hiraki, Xiaotian Tan, Eve H. Shikanov, Robert N. Kent, Carole Parent, Xudong Fan, Ariella Shikanov, Matthew L. Kutys, Brendon M. Baker   +17 more
wiley   +1 more source

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

Advanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang, Cancan Yao, Yan Chen, Ke Cai, Zhouping Lu, Boxuan Wu, Kun Yu, Yan Shi, Jianyuan Zhao, Xiangyu Zhou   +9 more
wiley   +1 more source

Derived Demand for Cattle Feeding Inputs

Derived demand relationships among four weight categories of feeder cattle entering Texas feedlots and their feed consumed are examined using a generalized McFadden dual cost function.
Mathews, Kenneth H., Jr., Jones, Keithly G., Arnade, Carlos A.   +2 more
core   +2 more sources

Voltage Drop and Power Loss Mitigation on SGN-14 via SGN-15 Feeder Design in Distribution System ULP Magelang

Aviation Electronics, Information Technology, Telecommunications, Electricals, Controls
Feeder SGN-14 of PT PLN (Persero) ULP Magelang operates under overload conditions, significantly degrading voltage quality and increasing technical losses.
Haqrodji Prabu Yasya, Deria Pravitasari, Agung Trihasto, Andriyatna Agung Kurniawan   +3 more
doaj   +1 more source

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

Full‐Body AI Agent: A Perspective on Multi‐Scale Collaborative AI for Systemic Biology and Precision Medicine

Advanced Science, EarlyView.
We propose the Full‐Body AI Agent, a multi‐scale collaborative framework with 7 biological‐layer agents. It unifies multi‐omics/clinical data via standardized protocols, enabling phenotype‐guided closed‐loop reasoning, quantitative evaluation, and LLM safeguards, with promising applications in tumor metastasis modeling and precision drug development ...
Aoqi Wang, Jiajia Liu, Jianguo Wen, Yangyang Luo, Zhiwei Fan, Liren Yang, Xi Hu, Ruihan Luo, Yankai Yu, Sophia Li, Weiling Zhao, Xiaobo Zhou   +11 more
wiley   +1 more source

Effects of feeder design, wet-dry feeder adjustment strategy, and diet type on the growth performance and carcass characteristics of growing-finishing pigs [PDF]

, 2010
A total of 1,287 pigs (PIC 337 × 1050, initially 82.7 lb) were used to compare the effects of a conventional dry feeder, 3 wet-dry feeder adjustment strategies, and 2 diet types on growing-finishing pig performance.
J R Bergstrom, Goodband, Robert D., Joel M DeRouchey, Bergstrom, J R, Michael D Tokach, DeRouchey, Joel M, Goodband, Robert D, Tokach, Michael D., Tokach, Michael D, Robert D Goodband, Nelssen, Jim L, Dritz, Steven S, Steven S Dritz, Bergstrom, J.R., Nelssen, Jim L., Dritz, Steven S., Jim L Nelssen, DeRouchey, Joel M.   +17 more
core   +1 more source

Optimal design of ride-pooling as on-demand feeder services

Transportation Research Part B: Methodological
The technology-enabled ride-pooling (RP) is designed as an on-demand feeder service to connect remote areas to transit terminals (or activity centers). We propose the so-called ``hold-dispatch'' operation strategy, which imposes a target number of shared rides (termed the ride-pooling size) for each vehicle to enhance RP's transportation efficiency ...
Wenbo Fan, Weihua Gu, Meng Xu
openaire   +3 more sources

Study of Free‐Space Optical Quantum Network: Review and Prospectives

Advanced Science, EarlyView.
Free from the constraints of fiber connections, free‐space quantum network enables longer and more flexible quantum network connections. This review summarizes and comparatively analyzes free‐space quantum network experiments based on ground stations, satellites, and mobile platforms.
Hua‐Ying Liu, Zhenda Xie, Shining Zhu
wiley   +1 more source

ESTIMATING THE VALUE OF SOURCE VERIFICATION OF FEEDER CATTLE

Source-verified (SV) feeder cattle auctions were held in Bloomfield, Iowa, each October, November, and December from 1997-2000. This study compares price data from these SV auctions to traditional auctions at the same location to determine whether a ...
Yeboah, Godfred, Lawrence, John D.
core